The Journal of Neuroscience, March 15, 2006, ():
Glial Cells Dilate and Constrict Blood Vessels: A Mechanism of Neurovascular Coupling
J. Neurosci. Metea and Newman
26: 2862
Supplemental data
Files in this Data Supplement:
- supplemental material
-
Movie S1. Light-evoked vasodilation. Flickering light stimulation is indicated by the yellow circle. Movie shown 5X real time.
- supplemental material
-
Movie S2. Light-evoked vasoconstriction. Flickering light stimulation is indicated by the yellow circle. Movie shown 5X real time.
- supplemental material
-
Movie S3. Light-evoked sphincter-like vasoconstriction. Flickering light stimulation is indicated by the yellow circle. Movie shown 10X real time.
- supplemental material
-
Movie S4. Vasodilation evoked by photolysis of caged Ca2+ in an astrocyte. IR-DIC image of an arteriole (left) and Ca2+ fluorescence of the same region (right) were acquired nearly simultaneously. The UV uncaging flash triggered a propagated glial Ca2+ wave and vessel dilation. Uncaging flash is indicated by yellow lightning bolt. Movies shown 5X real time.
- supplemental material
-
Movie S5. Vasodilation evoked by arrival of a glial Ca2+ wave. The intercellular Ca2+ wave was triggered by pipette ejection of 200 uM ATP at the location and time indicated by the yellow pipette. Movie shown 5X real time.
