The Journal of Neuroscience, May 10, 2006, ():
Asymmetric Localization of Vangl2 and Fz3 Indicate Novel Mechanisms for Planar Cell Polarity in Mammals
J. Neurosci. Montcouquiol et al.
26: 5265
Supplemental data
Files in this Data Supplement:
- supplemental material
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Supplemental Figure 1. Vangl2 is asymmetrically localized in the embryonic cochlea
A. The same image as in Fig. 1C,D, but with the individual red and green channels illustrated. Arrowheads, arrows and asterisks are the same as in Fig. 1C. B. The same image as in Fig. 1E,F, but with the individual red and green channels illustrated. Arrowheads, arrows and asterisks are the same as in Fig. 1E. C. High magnification version of the image in Fig. 1C. Arrowheads, arrows and asterisks are the same as in Fig. 1C. D. High magnification version of the image in Fig. 1E. Arrowheads, arrows and asterisks are the same as in Fig. 1E. E. The same image as in Fig. 1G, but with the individual red and green channels illustrated. Arrowheads are the same as in Fig. 1G.
- supplemental material
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Supplemental Figure 2. Vangl2 is absent in mature cochlea
A-D. Luminal surface of the apical (A,B) and basal (C,D) regions of a P7 rat cochlea. Vangl2 expression is largely down-regulated at this stage. Vangl2 is present in the cytoplasm of IP and OP and some asymmetrical localization remains in the less mature apical part of the cochlea (A,B), in the IP and second row OHC (arrows).
- supplemental material
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Supplemental Figure 3. Localization of Vangl2 with N-cadherin and β1β2-tubulin
A. The same image as in Fig. 1M, but with the individual green and red channels illustrated. Arrows and arrowheads are the same as in Fig. 1M. B. The same image as in Fig. 1N, but with the individual green and red channels illustrated. Arrows and arrowheads are the same as in Fig. 1N.
