The Journal of Neuroscience, June 7, 2006, ():
Distinct Frequency-Dependent Regulation of Nerve Terminal Excitability and Synaptic Transmission by IA and IK Potassium Channels Revealed by Drosophila Shaker and Shab Mutations
J. Neurosci. Ueda and Wu
26: 6238
Supplemental data
Files in this Data Supplement:
- supplemental material
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Supplemental Figure. Muscle action potentials in WT, Shab, and Sh larvae.
Muscle action potentials were triggered by depolarizing current injection in the presence of Sr2+ (4 mM). (A) Superimposed traces showing a subthreshold response and an overshooting action potential (depolarization beyond 0 mV indicated by dotted lines). The amplitude and threshold of action potentials were similar among WT and both mutants, but the duration was significantly increased in Shab. (B) A suprathreshold muscle depolarization triggered only a single action potential in WT and Sh larvae, but evoked a train of action potentials in Shab muscles. and indicate subthreshold and suprathreshold depolarization, respectively.
