The Journal of Neuroscience, August 30, 2006, ():
Extinction Training in Conjunction with a Partial Agonist of the Glycine Site on the NMDA Receptor Erases Memory Trace
J. Neurosci. Mao et al.
26: 8892
Supplemental data
Files in this Data Supplement:
- supplemental material
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Supplemental figure 1. Representative photomicrograph illustrates placement of infusion needle tip in the LA.
Rats were implanted bilaterally with guide cannulae aimed at either the LA or BLA. After behavioral testing, the rats were perfused with 4% formaldehyde, and their brains were sectioned at 40 μm thickness stained for Nissl bodies and examined by light microscopy. Scale bar: 0.5 mm
- supplemental material
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Supplemental figure 2. Co-treatment of DCS with extinction training does not affect total amount of GluR1 levels.
Rats were conditioned, 24 h later they were infused with DCS (10 μg per side) bilaterally into the amygdala 30 min before extinction training. Twenty-four hours after extinction training, LA and BLA tissues were dissected out and the total GluR1 was measured in tissue homogenates. Fear conditioning and co-treatment of DCS with light-alone trials did not affect the total GluR1 levels.
