The Journal of Neuroscience, October 4, 2006, ():
Activity-Independent Regulation of Dendrite Patterning by Postsynaptic Density Protein PSD-95
J. Neurosci. Charych et al.
26: 10164
Supplemental data
Files in this Data Supplement:
- supplemental material
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Supplementary Figure 1. Flowchart of Branching model. (A) The number of primary dendrites, N, are drawn from Poisson distribution with intensity parameter L1(type). The expected number of primary dendrites are thus L1(type), where “type” denotes the cell-type (wildtype, cypin overexpressed, knockdown etc). The probability that a primary dendrite will branch is denoted by p, where p is dependent on the cell type only. The Poisson parameter for the third stage of the data generating process, L2, denotes the number of expected “excess” secondary branches. The number of secondary branches thus generated are denoted by Y. (B) A hippocampal pyramidal neuron is shown to illustrate the working definitions used to analyze dendritic branching. Three primary dendrites are depicted, each containing, from left to right, 0, 2, or 3 secondary dendrites. The proportion of primary dendrites that branch is 2/3, regardless of the number of secondary dendrites formed at a given branch point. The number of excess secondary dendrites is defined as the sum of all secondary dendrites emanating from a branch-point that already contains two secondary dendrites. As shown, only one secondary dendrite, emanating from the right-most primary dendrite, meets this criterion.
