The Journal of Neuroscience, November 22, 2006, ():
Molecular Markers of Neuronal Progenitors in the Embryonic Cerebellar Anlage
J. Neurosci. Morales and Hatten
26: 12226
Supplemental Data
Files in this Data Supplement:
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Supplementary Figure 1. Time-Line of Transcription Factor Expression in Precursor Cell Populations of the Embryonic Cerebellar Anlage. A “time line” from the day of closure of the neural tube (E9.5), at left, to birth, at right, is given, with the period of cerebellar histogenesis expanded. The time of expression of transcription factors for each class of neural progenitor is given above the line. Progenitors of the neurons of the cerebellar nuclei (blue) are the first pool of progenitors, generated on E10.25, followed by the progenitors for the cortical Purkinje cells (red), on E11.5, and the movement of progenitors of the cortical granule cells (green) as well as progenitors destined for the cerebellar nuclei, pre-cerebellar nuclei and other brainstem nuclei of the “cerebellar system” onto the surface of the anlage, beginning on about E12.5. Between E12.5 and E16, EGL cells spread over the surface of the anlagen. Between E13 and E15, CN precursors move off of the surface and form the cerebellar nuclei. For details, see text.
