The Journal of Neuroscience, March 28, 2007, ():
Ethanol Induces Long-Term Facilitation of NR2B-NMDA Receptor Activity in the Dorsal Striatum: Implications for Alcohol Drinking Behavior
J. Neurosci. Wang et al.
27: 3593
Supplemental Data
Files in this Data Supplement:
- supplemental material
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Supplemental Figure 1. Ethanol-mediated induction of LTF in the absence of the tyrosine phosphatase inhibitor sodium orthovanadate. A, Time course of NMDAR EPSCs before, during and after ethanol (100 mM) application in absence of the tyrosine phosphatase inhibitor sodium orthovanadate. The horizontal bar indicates ethanol application. n = 12 slices. The inset shows sample traces at times 1, 2 and 3. Calibration, 100 ms, 100 pA. B, Bar graph comparing effects of ethanol on NMDAR EPSCs in the presence and absence of the tyrosine phosphatase inhibitor Na2VO4 (sodium orthovanadate), # and * p < 0.05 vs. baseline by one-way ANOVA.
- supplemental material
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Supplemental Figure 2. Mean cumulative active lever presses for ethanol after infusion of vehicle, 1.5 ng of PP2 or ifenprodil. Data are expressed as mean ± SEM of cumulative number of lever presses by intervals of 5 min (n = 11 rats).
