The Journal of Neuroscience, June 13, 2007, ():
A Calcium-Activated Nonselective Cation Conductance Underlies the Plateau Potential in Rat Substantia Nigra GABAergic Neurons
J. Neurosci. Lee and Tepper
27: 6531
Supplemental Data
Files in this Data Supplement:
- supplemental material
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Supplementary Figure 1: The plateau potential could be observed with potassium gluconate replaced by potassium methyl sulfate in the pipette solution. A. A nigral GABAergic neuron exhibits regular spiking spontaneous activity with potassium methyl sulfate-containing pipette solution. B. When a depolarizing current pulse is delivered from rest, the neuron responds with a prolonged increase in firing rate outlasting the depolarizing current pulse. C. When held hyperpolarized, the neuron responds to a depolarizing current pulse with a plateau potential that outlasts the depolarizing current. These results suggest that a plateau with properties which are similar or identical to those observed with potassium gluconate-containing pipette solution can be observed with potassium methyl sulfate-containing pipette solution.
