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The Journal of Neuroscience, August 8, 2007, ():
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Role of Calcineurin in Nicotine-Mediated Locomotor Sensitization
J. Neurosci. Addy et al. 27: 8571Supplemental Data
Files in this Data Supplement:
- supplemental material - Supplemental Figure 1: Across session locomotor activity in nicotine-treated rats. Total locomotor activity in a 60 min period following subcutaneous injection of saline or nicotine (0.35 mg/kg) during (A) systemic administration of cyclosporine (15 mg/kg) or (B) intra-VTA administration of cyclosporine (1 ?g/side/day). Peak locomotor activity in each session was observed in the first 15 min following subcutaneous drug administration.
- supplemental material - Supplemental Figure 2: Intra-VTA cyclosporine administration does not alter baseline locomotor activity. Analysis of total activity in the 30 min habituation period prior to subcutaneous administration of saline or nicotine (0.35 mg/kg). Peak activity was observed in the first 5 min of the habituation session and decreased over a 30 min period on each day of testing. A repeated measure ANOVA for each day of testing demonstrated that there was no effect of treatment on baseline locomotor activity during habituation sessions.
- supplemental material - Supplemental Figure 3: Cannula placements in the VTA and nucleus accumbens. Representative cannula placements in the VTA (A) and nucleus accumbens (B) for cyclosporine and FK506 infusion (both at 1 ?g/side/day).
This Article Abstract Full Text Submit an eLetter Services Email this article to a friend Alert me to new issues of the journal Citing Articles Citing Articles via Web of Science (2)
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