 |
 Previous Article | Next Article 
Journal of Neuroscience, Vol 12, 3115-3138, Copyright © 1992 by Society for Neuroscience
Differential imaging of ocular dominance and orientation selectivity in monkey striate cortex
GG Blasdel
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115.
Differential images of ocular dominance, acquired by comparing responses to
the two eyes, reveal dark and light bands where cortical cells are
dominated by the right and left eyes. These include most (but not all)
histochemically stained cytochrome oxidase blobs in their centers.
Differential images of orientation, acquired by comparing responses to
orthogonal orientations, reveal dark and light bands that are reminiscent
of the "orientation columns" reported earlier, on the basis of
2-deoxyglucose (2DG) autoradiograms (Hubel et al., 1978). However, they are
shorter and more fragmented because they do not include regions lacking
selectivity for orientation. Even though these "bands" derive from
orientation-selective areas, comparisons with differential images of other
orientations reveal that regions along their centers prefer different
orientations. Hence, the orientation preferences inferred from "bands" in
single differential images, or single 2DG autoradiograms, are not
necessarily incorrect. Interactions between ocular dominance and
orientation were investigated by comparing differential images of
orientation obtained with binocular and monocular stimulation, as well as
by comparing differential images of ocular dominance obtained with
different orientations. In both cases, the elicited interactions were
minimal, indicating a remarkable and unexpected independence that
subsequent experiments revealed arises, at least in part, from a lateral
segregation of regions most selective for one eye and regions most
selective for one orientation, in the centers and edges of ocular dominance
columns. Since this can also be viewed as a lateral correlation between
binocularity and orientation selectivity, it fits with the simultaneous
emergence of these properties in layers receiving input from layer 4c, and
suggests that each of these properties requires the other.
This article has been cited by other articles:
|
|
|
|
 
G. Purushothaman, I. Khaytin, and V. A. Casagrande
Quantification of Optical Images of Cortical Responses for Inferring Functional Maps
J Neurophysiol,
May 1, 2009;
101(5):
2708 - 2724.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. I. Chelaru and V. Dragoi
Efficient coding in heterogeneous neuronal populations
PNAS,
October 21, 2008;
105(42):
16344 - 16349.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Yacoub, N. Harel, and K. Ugurbil
High-field fMRI unveils orientation columns in humans
PNAS,
July 29, 2008;
105(30):
10607 - 10612.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. P. Issa, A. Rosenberg, and T. R. Husson
Models and Measurements of Functional Maps in V1
J Neurophysiol,
June 1, 2008;
99(6):
2745 - 2754.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S.-G. Kim and M. Fukuda
Lessons from fMRI about Mapping Cortical Columns
Neuroscientist,
June 1, 2008;
14(3):
287 - 299.
[Abstract]
[PDF]
|
|
|
|
|
|
|
H. D. Lu and A. W. Roe
Functional Organization of Color Domains in V1 and V2 of Macaque Monkey Revealed by Optical Imaging
Cereb Cortex,
March 1, 2008;
18(3):
516 - 533.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. A. Orban
Higher Order Visual Processing in Macaque Extrastriate Cortex
Physiol Rev,
January 1, 2008;
88(1):
59 - 89.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Wielaard and P. Sajda
Dependence of Response Properties on Sparse Connectivity in a Spiking Neuron Model of the Lateral Geniculate Nucleus
J Neurophysiol,
December 1, 2007;
98(6):
3292 - 3308.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C.-H. Moon, M. Fukuda, S.-H. Park, and S.-G. Kim
Neural Interpretation of Blood Oxygenation Level-Dependent fMRI Maps at Submillimeter Columnar Resolution
J. Neurosci.,
June 27, 2007;
27(26):
6892 - 6902.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Fukuda, C.-H. Moon, P. Wang, and S.-G. Kim
Mapping Iso-Orientation Columns by Contrast Agent-Enhanced Functional Magnetic Resonance Imaging: Reproducibility, Specificity, and Evaluation by Optical Imaging of Intrinsic Signal.
J. Neurosci.,
November 15, 2006;
26(46):
11821 - 11832.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Wielaard and P. Sajda
Circuitry and the Classification of Simple and Complex Cells in V1
J Neurophysiol,
November 1, 2006;
96(5):
2739 - 2749.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Wielaard and P. Sajda
Extraclassical Receptive Field Phenomena and Short-Range Connectivity in V1
Cereb Cortex,
November 1, 2006;
16(11):
1531 - 1545.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. V. Rangan, D. Cai, and D. W. McLaughlin
Inaugural Article: Modeling the spatiotemporal cortical activity associated with the line-motion illusion in primary visual cortex
PNAS,
December 27, 2005;
102(52):
18793 - 18800.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. C Horton and D. L Adams
The cortical column: a structure without a function
Phil Trans R Soc B,
April 29, 2005;
360(1456):
837 - 862.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Cai, A. V. Rangan, and D. W. McLaughlin
Architectural and synaptic mechanisms underlying coherent spontaneous activity in V1
PNAS,
April 19, 2005;
102(16):
5868 - 5873.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Naselaris, H. Merchant, B. Amirikian, and A. P. Georgopoulos
Spatial Reconstruction of Trajectories of an Array of Recording Microelectrodes
J Neurophysiol,
April 1, 2005;
93(4):
2318 - 2330.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Sirovich and R. Uglesich
The organization of orientation and spatial frequency in primary visual cortex
PNAS,
November 30, 2004;
101(48):
16941 - 16946.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. M. Friedman, L. M. Chen, and A. W. Roe
Modality maps within primate somatosensory cortex
PNAS,
August 24, 2004;
101(34):
12724 - 12729.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
X. Xu, W. Bosking, G. Sary, J. Stefansic, D. Shima, and V. Casagrande
Functional Organization of Visual Cortex in the Owl Monkey
J. Neurosci.,
July 14, 2004;
24(28):
6237 - 6247.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Cai, L. Tao, M. Shelley, and D. W. McLaughlin
An effective kinetic representation of fluctuation-driven neuronal networks with application to simple and complex cells in visual cortex
PNAS,
May 18, 2004;
101(20):
7757 - 7762.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
X. Xu, C. E. Collins, P. M. Kaskan, I. Khaytin, J. H. Kaas, and V. A. Casagrande
Optical imaging of visually evoked responses in prosimian primates reveals conserved features of the middle temporal visual area
PNAS,
February 24, 2004;
101(8):
2566 - 2571.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Tao, M. Shelley, D. McLaughlin, and R. Shapley
An egalitarian network model for the emergence of simple and complex cells in visual cortex
PNAS,
January 6, 2004;
101(1):
366 - 371.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Grossberg and A. Seitz
Laminar Development of Receptive Fields, Maps and Columns in Visual Cortex: The Coordinating Role of the Subplate
Cereb Cortex,
August 1, 2003;
13(8):
852 - 863.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. S. Lund, A. Angelucci, and P. C. Bressloff
Anatomical Substrates for Functional Columns in Macaque Monkey Primary Visual Cortex
Cereb Cortex,
January 1, 2003;
13(1):
15 - 24.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. D. Freeman
Cortical Columns: A Multi-parameter Examination
Cereb Cortex,
January 1, 2003;
13(1):
70 - 72.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. C. Lyon, X. Xu, V. A. Casagrande, J. D. Stefansic, D. Shima, and J. H. Kaas
Inaugural Article: Optical imaging reveals retinotopic organization of dorsal V3 in New World owl monkeys
PNAS,
November 26, 2002;
99(24):
15735 - 15742.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Blasdel and D. Campbell
Functional Retinotopy of Monkey Visual Cortex
J. Neurosci.,
October 15, 2001;
21(20):
8286 - 8301.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. J. Wielaard, M. Shelley, D. McLaughlin, and R. Shapley
How Simple Cells Are Made in a Nonlinear Network Model of the Visual Cortex
J. Neurosci.,
July 15, 2001;
21(14):
5203 - 5211.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. C. Sincich and G. G. Blasdel
Oriented Axon Projections in Primary Visual Cortex of the Monkey
J. Neurosci.,
June 15, 2001;
21(12):
4416 - 4426.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Shtoyerman, A. Arieli, H. Slovin, I. Vanzetta, and A. Grinvald
Long-Term Optical Imaging and Spectroscopy Reveal Mechanisms Underlying the Intrinsic Signal and Stability of Cortical Maps in V1 of Behaving Monkeys
J. Neurosci.,
November 1, 2000;
20(21):
8111 - 8121.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. McLaughlin, R. Shapley, M. Shelley, and D. J. Wielaard
A neuronal network model of macaque primary visual cortex (V1): Orientation selectivity and dynamics in the input layer 4Calpha
PNAS,
June 23, 2000;
(2000)
110135097.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
S. L. Macknik, S. Martinez-Conde, and M. M. Haglund
The role of spatiotemporal edges in visibility and visual masking
PNAS,
June 13, 2000;
(2000)
110142097.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
A. Shmuel and A. Grinvald
Coexistence of linear zones and pinwheels within orientation maps in cat visual cortex
PNAS,
May 9, 2000;
97(10):
5568 - 5573.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. L. Macknik and M. M. Haglund
Optical images of visible and invisible percepts in the primary visual cortex of primates
PNAS,
December 21, 1999;
96(26):
15208 - 15210.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. W. Roe and D. Y. Ts'o
Specificity of Color Connectivity Between Primate V1 and V2
J Neurophysiol,
November 1, 1999;
82(5):
2719 - 2730.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. M. Everson, A. K. Prashanth, M. Gabbay, B. W. Knight, L. Sirovich, and E. Kaplan
Representation of spatial frequency and orientation in the visual cortex
PNAS,
July 7, 1998;
95(14):
8334 - 8338.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Hubener, D. Shoham, A. Grinvald, and T. Bonhoeffer
Spatial Relationships among Three Columnar Systems in Cat Area 17
J. Neurosci.,
December 1, 1997;
17(23):
9270 - 9284.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. C. Crair, E. S. Ruthazer, D. C. Gillespie, and M. P. Stryker
Ocular Dominance Peaks at Pinwheel Center Singularities of the Orientation Map in Cat Visual Cortex
J Neurophysiol,
June 1, 1997;
77(6):
3381 - 3385.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Chaudhuri, J. Nissanov, S. Larocque, and L. Rioux
Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 mRNA and protein expression
PNAS,
March 18, 1997;
94(6):
2671 - 2675.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. McLaughlin, R. Shapley, M. Shelley, and D. J. Wielaard
A neuronal network model of macaque primary visual cortex (V1): Orientation selectivity and dynamics in the input layer 4Calpha
PNAS,
July 5, 2000;
97(14):
8087 - 8092.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. L. Macknik, S. Martinez-Conde, and M. M. Haglund
The role of spatiotemporal edges in visibility and visual masking
PNAS,
June 20, 2000;
97(13):
7556 - 7560.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
