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Volume 17, Number 11,
Issue of June 1, 1997
pp. 4302-4311
Copyright ©1997 Society for Neuroscience
The Fusiform Face Area: A Module in Human Extrastriate Cortex
Specialized for Face Perception
Received Dec. 30, 1996; revised Feb. 26, 1997; accepted March 13, 1997.
Nancy Kanwisher1, 2,
Josh McDermott1, 2, and
Marvin M. Chun2, 3
1 Department of Psychology, Harvard University,
Cambridge, Massachusetts 02138, 2 Massachusetts General
Hospital NMR Center, Charlestown, Massachusetts 02129, and
3 Department of Psychology, Yale University, New Haven,
Connecticut 06520-8205
Using functional magnetic resonance imaging (fMRI), we found an
area in the fusiform gyrus in 12 of the 15 subjects tested that was
significantly more active when the subjects viewed faces than when they
viewed assorted common objects. This face activation was used to define
a specific region of interest individually for each subject, within
which several new tests of face specificity were run. In each of five
subjects tested, the predefined candidate "face area" also
responded significantly more strongly to passive viewing of (1) intact
than scrambled two-tone faces, (2) full front-view face photos than
front-view photos of houses, and (in a different set of five subjects)
(3) three-quarter-view face photos (with hair concealed) than photos of
human hands; it also responded more strongly during (4) a consecutive
matching task performed on three-quarter-view faces versus hands. Our
technique of running multiple tests applied to the same region defined
functionally within individual subjects provides a solution to two
common problems in functional imaging: (1) the requirement to correct
for multiple statistical comparisons and (2) the inevitable ambiguity
in the interpretation of any study in which only two or three
conditions are compared. Our data allow us to reject alternative
accounts of the function of the fusiform face area (area "FF") that
appeal to visual attention, subordinate-level classification, or
general processing of any animate or human forms, demonstrating that
this region is selectively involved in the perception of
faces.
Key words:
extrastriate cortex;
face perception;
functional MRI;
fusiform gyrus;
ventral visual pathway;
object recognition
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T. M. Mitchell, S. V. Shinkareva, A. Carlson, K.-M. Chang, V. L. Malave, R. A. Mason, and M. A. Just
Predicting Human Brain Activity Associated with the Meanings of Nouns
Science,
May 30, 2008;
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E. J. Barbeau, M. J. Taylor, J. Regis, P. Marquis, P. Chauvel, and C. Liegeois-Chauvel
Spatio temporal Dynamics of Face Recognition
Cereb Cortex,
May 1, 2008;
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M. Gur and D. M. Snodderly
Physiological differences between neurons in layer 2 and layer 3 of primary visual cortex (V1) of alert macaque monkeys
J. Physiol.,
May 1, 2008;
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[Abstract]
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F. Hadj-Bouziane, A. H. Bell, T. A. Knusten, L. G. Ungerleider, and R. B. H. Tootell
Perception of emotional expressions is independent of face selectivity in monkey inferior temporal cortex
PNAS,
April 8, 2008;
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5591 - 5596.
[Abstract]
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M. L. LoPresti, K. Schon, M. D. Tricarico, J. D. Swisher, K. A. Celone, and C. E. Stern
Working Memory for Social Cues Recruits Orbitofrontal Cortex and Amygdala: A Functional Magnetic Resonance Imaging Study of Delayed Matching to Sample for Emotional Expressions
J. Neurosci.,
April 2, 2008;
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J. Y. Chiao, R. B. Adams Jr, P. U. Tse, W. T. Lowenthal, J. A. Richeson, and N. Ambady
Knowing Who's Boss: fMRI and ERP Investigations of Social Dominance Perception
Group Processes Intergroup Relations,
April 1, 2008;
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[Abstract]
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J. A. Richeson, A. R. Todd, S. Trawalter, and A. A. Baird
Eye-Gaze Direction Modulates Race-Related Amygdala Activity
Group Processes Intergroup Relations,
April 1, 2008;
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233 - 246.
[Abstract]
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R. Grabner, F. Popotnig, S. Ropele, C. Neuper, F. Gorani, K. Petrovic, F. Ebner, S. Strasser-Fuchs, F. Fazekas, and C. Enzinger
Brain activation patterns elicited by the `Faces Symbol Test' -- a pilot fMRI study
Multiple Sclerosis,
April 1, 2008;
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[Abstract]
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I. A. J. van Kooten, S. J. M. C. Palmen, P. von Cappeln, H. W. M. Steinbusch, H. Korr, H. Heinsen, P. R. Hof, H. van Engeland, and C. Schmitz
Neurons in the fusiform gyrus are fewer and smaller in autism
Brain,
April 1, 2008;
131(4):
987 - 999.
[Abstract]
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N. M. Kleinhans, T. Richards, L. Sterling, K. C. Stegbauer, R. Mahurin, L. C. Johnson, J. Greenson, G. Dawson, and E. Aylward
Abnormal functional connectivity in autism spectrum disorders during face processing
Brain,
April 1, 2008;
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H. Xu, P. Dayan, R. M. Lipkin, and N. Qian
Adaptation across the Cortical Hierarchy: Low-Level Curve Adaptation Affects High-Level Facial-Expression Judgments
J. Neurosci.,
March 26, 2008;
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D. Rudrauf, O. David, J.-P. Lachaux, C. K. Kovach, J. Martinerie, B. Renault, and A. Damasio
Rapid Interactions between the Ventral Visual Stream and Emotion-Related Structures Rely on a Two-Pathway Architecture
J. Neurosci.,
March 12, 2008;
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[Abstract]
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