QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (28) Citing Articles via Google Scholar Google Scholar Articles by Clemens, S. Articles by Simmers, J. Search for Related Content PubMed PubMed Citation Articles by Clemens, S. Articles by Simmers, J.

 Previous Article

The Journal of Neuroscience, April 1, 1998, 18(7):2788-2799

In Vivo Modulation of Interacting Central Pattern Generators in Lobster Stomatogastric Ganglion: Influence of Feeding and Partial Pressure of Oxygen

Stefan Clemens¹, Jean-Charles Massabuau², Alexia Legeay², Pierre Meyrand¹, and John Simmers¹

¹ Laboratoire de Neurobiologie des Réseaux Université de Bordeaux I and Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5816, F-33120 Arcachon, France, and ² Laboratoire d'Ecophysiologie et Ecotoxicologie des Systèmes Aquatiques Université de Bordeaux I and Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5805, F-33120 Arcachon, France

The stomatogastric ganglion (STG) of the European lobster Homarus gammarus contains two rhythm-generating networks (the gastric and pyloric circuits) that in resting, unfed animals produce two distinct, yet strongly interacting, motor patterns. By using simultaneous EMG recordings from the gastric and pyloric muscles in vivo, we found that after feeding, the gastropyloric interaction disappears as the two networks express accelerated motor rhythms. The return to control levels of network activity occurs progressively over the following 1-2 d and is associated with a gradual reappearance of the gastropyloric interaction. In parallel with this change in network activity is an alteration of oxygen levels in the blood. In resting, unfed animals, arterial partial pressure of oxygen (PO₂) is most often between 1 and 2 kPa and then doubles within 1 hr after feeding, before returning to control values some 24 hr later. In vivo, experimental prevention of the arterial PO₂ increase after feeding leads to a slowing of pyloric rhythmicity toward control values and a reappearance of the gastropyloric interaction, without apparent effect on gastric network operation. Using in vitro preparations of the stomatogastric nervous system and by changing oxygen levels uniquely at the level of the STG within the range observed in the intact animal, we were able to mimic most of the effects observed in vivo. Our data indicate that the gastropyloric interaction appears only during a "free run" mode of foregut activity and that the coordinated operation of multiple neural networks may be modulated by local changes in oxygenation.

Key words: lobster; feeding behavior; stomatogastric ganglion; neural network; synaptic interaction; oxygen; hypoxia; modulation; internetwork coordination

---

Copyright © 1998 Society for Neuroscience  0270-6474/98/1872788-12$05.00/0

This article has been cited by other articles:

				D. M. Blitz and M. P. Nusbaum State-Dependent Presynaptic Inhibition Regulates Central Pattern Generator Feedback to Descending Inputs J. Neurosci., September 17, 2008; 28(38): 9564 - 9574. [Abstract] [Full Text] [PDF]

				A. K. Tryba, F. Pena, S. P. Lieske, J.-C. Viemari, M. Thoby-Brisson, and J.-M. Ramirez Differential Modulation of Neural Network and Pacemaker Activity Underlying Eupnea and Sigh-Breathing Activities J Neurophysiol, May 1, 2008; 99(5): 2114 - 2125. [Abstract] [Full Text] [PDF]

				S. R. Saideman, D. M. Blitz, and M. P. Nusbaum Convergent Motor Patterns from Divergent Circuits J. Neurosci., June 20, 2007; 27(25): 6664 - 6674. [Abstract] [Full Text] [PDF]

				I. J. McGaw Feeding and digestion in low salinity in an osmoconforming crab, Cancer gracilis II. Gastric evacuation and motility J. Exp. Biol., October 1, 2006; 209(19): 3777 - 3785. [Abstract] [Full Text] [PDF]

				I. J. McGaw Does feeding limit cardiovascular modulation in the Dungeness crab Cancer magister during hypoxia? J. Exp. Biol., January 1, 2005; 208(1): 83 - 91. [Abstract] [Full Text] [PDF]

				E. Mente, A. Legeay, D. F. Houlihan, and J.-C. Massabuau Influence of oxygen partial pressures on protein synthesis in feeding crabs Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2003; 284(2): R500 - R510. [Abstract] [Full Text] [PDF]

				J Forgue, A Legeay, and J. Massabuau Is the resting rate of oxygen consumption of locomotor muscles in crustaceans limited by the low blood oxygenation strategy? J. Exp. Biol., January 3, 2001; 204(5): 933 - 940. [Abstract] [PDF]

				R. F. Jansen, A. W. Pieneman, and A. t. Maat Pattern Generation in the Buccal System of Freely Behaving Lymnaea stagnalis J Neurophysiol, December 1, 1999; 82(6): 3378 - 3391. [Abstract] [Full Text] [PDF]

				M. Bartos, Y. Manor, F. Nadim, E. Marder, and M. P. Nusbaum Coordination of Fast and Slow Rhythmic Neuronal Circuits J. Neurosci., August 1, 1999; 19(15): 6650 - 6660. [Abstract] [Full Text] [PDF]

				S Clemens, J. Massabuau, P Meyrand, and J Simmers Changes in motor network expression related to moulting behaviour in lobster: role of moult-induced deep hypoxia J. Exp. Biol., January 4, 1999; 202(7): 817 - 827. [Abstract] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help