WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (16)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nicholson, D. A.
Right arrow Articles by Freeman, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nicholson, D. A.
Right arrow Articles by Freeman, J. H., Jr
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*Seniors' Health

 Previous Article  |  Next Article 

The Journal of Neuroscience, November 1, 2000, 20(21):8218-8226

Developmental Changes in Eye-Blink Conditioning and Neuronal Activity in the Inferior Olive

Daniel A. Nicholson and John H. Freeman Jr

Department of Psychology, University of Iowa, Iowa City, Iowa 52242

Neuronal activity was recorded in the dorsal accessory inferior olive in infant rats during classical conditioning of the eye-blink response. The percentage and amplitude of eye-blink conditioned responses (CRs) increased as a function of age. The magnitude of the neuronal response to the unconditioned stimulus (US) decreased with age. There were also age-specific modifications of US-elicited inferior olive neuronal activity during paired trials in which a conditioned eye-blink response was performed. The results indicate that the development of the conditioned eye-blink response may depend on dynamic interactions between multiple developmental processes within the eye-blink circuitry. Differences in the functional maturity of olivo-cerebellar pathways may limit the induction of plasticity in the cerebellum and thereby limit the development of eye-blink conditioned responses.

Key words: ontogeny; brainstem; olive; learning; conditioning; eyeblink

Copyright © 2000 Society for Neuroscience  0270-6474/00/20218218-09$05.00/0


This article has been cited by other articles:


Home page
 Behav Cogn Neurosci RevHome page
J. H. Freeman Jr. and D. A. Nicholson
Developmental Changes in the Neural Mechanisms of Eyeblink Conditioning
Behav Cogn Neurosci Rev, March 1, 2004; 3(1): 3 - 13.
[Abstract] [PDF]

Home page
 J. Neurophysiol.Home page
D. A. Nicholson and J. H. Freeman Jr.
Developmental Changes in Evoked Purkinje Cell Complex Spike Responses
J Neurophysiol, October 1, 2003; 90(4): 2349 - 2357.
[Abstract] [Full Text] [PDF]

Home page
 Learn. Mem.Home page
J. H. Freeman Jr. and A. S. Muckler
Developmental Changes in Eyeblink Conditioning and Neuronal Activity in the Pontine Nuclei
Learn. Mem., September 1, 2003; 10(5): 337 - 345.
[Abstract] [Full Text] [PDF]


-
-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2009 by Society for Neuroscience ONLINE ISSN: 1529-2401
-