 |
 Previous Article | Next Article 
The Journal of Neuroscience, July 1, 2001, 21(13):4809-4821
Perceptually Bistable Three-Dimensional Figures Evoke High
Choice Probabilities in Cortical Area MT
Jonathan V.
Dodd,
Kristine
Krug,
Bruce G.
Cumming, and
Andrew J.
Parker
University Laboratory of Physiology, Oxford OX1 3PT, United Kingdom
The role of the primate middle temporal area (MT) in depth
perception was examined by considering the trial-to-trial correlations between neuronal activity and reported depth sensations. A set of
moving random dots portrayed a cylinder rotating about its principal
axis. In this structure-from-motion stimulus, the direction of rotation
is ambiguous and the resulting percept undergoes spontaneous fluctuations. The stimulus can be rendered unambiguous by the addition
of binocular disparities. We trained monkeys to report the direction of
rotation in a set of these stimuli, one of which had zero disparity.
Many disparity-selective neurons in area MT are selective for the
direction of rotation defined by disparity. Across repeated
presentations of the ambiguous (zero-disparity) stimulus, there was a
correlation between neuronal firing and the reported direction of
rotation, as found by Bradley et al. (1998).
Quantification of this effect using choice probabilities (Britten et al., 1996) allowed us to demonstrate that
the correlation cannot be explained by eye movements, behavioral
biases, or attention to spatial location. MT neurons therefore appear
to be involved in the perceptual decision process. The mean choice
probability (0.67) was substantially larger than that reported for MT
neurons in a direction discrimination task (Britten et al.,
1996). This implies that MT neurons make a different
contribution to the two tasks. For the depth task, either the pool of
neurons used is smaller or the correlation between neurons in the pool
is larger.
Key words:
depth perception; kinetic depth effect; choice
probability; cortical area MT; awake macaque; electrophysiology; stereopsis
Copyright © 2001 Society for Neuroscience 0270-6474/01/21134809-13$05.00/0
This article has been cited by other articles:
|
|
|
|
 
T. M. Herrington and J. A. Assad
Neural Activity in the Middle Temporal Area and Lateral Intraparietal Area during Endogenously Cued Shifts of Attention
J. Neurosci.,
November 11, 2009;
29(45):
14160 - 14176.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. A. Chowdhury, K. Takahashi, G. C. DeAngelis, and D. E. Angelaki
Does the Middle Temporal Area Carry Vestibular Signals Related to Self-Motion?
J. Neurosci.,
September 23, 2009;
29(38):
12020 - 12030.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. M. Yu, J. P. Cunningham, G. Santhanam, S. I. Ryu, K. V. Shenoy, and M. Sahani
Gaussian-Process Factor Analysis for Low-Dimensional Single-Trial Analysis of Neural Population Activity
J Neurophysiol,
July 1, 2009;
102(1):
614 - 635.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. R. Cohen and W. T. Newsome
Estimates of the Contribution of Single Neurons to Perception Depend on Timescale and Noise Correlation
J. Neurosci.,
May 20, 2009;
29(20):
6635 - 6648.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. M. Herrington, N. Y. Masse, K. J. Hachmeh, J. E. T. Smith, J. A. Assad, and E. P. Cook
The Effect of Microsaccades on the Correlation between Neural Activity and Behavior in Middle Temporal, Ventral Intraparietal, and Lateral Intraparietal Areas
J. Neurosci.,
May 6, 2009;
29(18):
5793 - 5805.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. M. Ghose and I. T. Harrison
Temporal Precision of Neuronal Information in a Rapid Perceptual Judgment
J Neurophysiol,
March 1, 2009;
101(3):
1480 - 1493.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Mojzisch and K. Krug
Cells, circuits, and choices: Social influences on perceptual decision making
Cogn Affect Behav Neurosci,
December 1, 2008;
8(4):
498 - 508.
[Abstract]
[PDF]
|
|
|
|
|
|
|
P. Neri and D. M. Levi
Evidence for Joint Encoding of Motion and Disparity in Human Visual Perception
J Neurophysiol,
December 1, 2008;
100(6):
3117 - 3133.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Krug, E. Brunskill, A. Scarna, G. M Goodwin, and A. J Parker
Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder
Proc R Soc B,
August 22, 2008;
275(1645):
1839 - 1848.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Hesselmann, C. A. Kell, E. Eger, and A. Kleinschmidt
Spontaneous local variations in ongoing neural activity bias perceptual decisions
PNAS,
August 5, 2008;
105(31):
10984 - 10989.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Kim and M. A. Basso
Saccade Target Selection in the Superior Colliculus: A Signal Detection Theory Approach
J. Neurosci.,
March 19, 2008;
28(12):
2991 - 3007.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Y. Masse and E. P. Cook
The Effect of Middle Temporal Spike Phase on Sensory Encoding and Correlates with Behavior during a Motion-Detection Task
J. Neurosci.,
February 6, 2008;
28(6):
1343 - 1355.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. A. Chowdhury, D. L. Christiansen, M. L. Morgan, and G. C. DeAngelis
Effect of Vertical Disparities on Depth Representation in Macaque Monkeys: MT Physiology and Behavior
J Neurophysiol,
February 1, 2008;
99(2):
876 - 887.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. P. Cook, J. A. Guest, Y. Liang, N. Y. Masse, and C. M. Colbert
Dendrite-to-Soma Input/Output Function of Continuous Time-Varying Signals in Hippocampal CA1 Pyramidal Neurons
J Neurophysiol,
November 1, 2007;
98(5):
2943 - 2955.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. W. Roe, A. J. Parker, R. T. Born, and G. C. DeAngelis
Disparity Channels in Early Vision
J. Neurosci.,
October 31, 2007;
27(44):
11820 - 11831.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Palmer, S.-Y. Cheng, and E. Seidemann
Linking Neuronal and Behavioral Performance in a Reaction-Time Visual Detection Task
J. Neurosci.,
July 25, 2007;
27(30):
8122 - 8137.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Maier, N. K. Logothetis, and D. A. Leopold
Context-dependent perceptual modulation of single neurons in primate visual cortex
PNAS,
March 27, 2007;
104(13):
5620 - 5625.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. E. B. Mruczek and D. L. Sheinberg
Activity of Inferior Temporal Cortical Neurons Predicts Recognition Choice Behavior and Recognition Time during Visual Search
J. Neurosci.,
March 14, 2007;
27(11):
2825 - 2836.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Thielscher and L. Pessoa
Neural Correlates of Perceptual Choice and Decision Making during Fear-Disgust Discrimination
J. Neurosci.,
March 14, 2007;
27(11):
2908 - 2917.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Pessoa and S. Padmala
Decoding Near-Threshold Perception of Fear from Distributed Single-Trial Brain Activation
Cereb Cortex,
March 1, 2007;
17(3):
691 - 701.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. J. McKeeff and F. Tong
The Timing of Perceptual Decisions for Ambiguous Face Stimuli in the Human Ventral Visual Cortex
Cereb Cortex,
March 1, 2007;
17(3):
669 - 678.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Chandrasekaran, V. Canon, J. C. Dahmen, Z. Kourtzi, and A. E. Welchman
Neural Correlates of Disparity-Defined Shape Discrimination in the Human Brain
J Neurophysiol,
February 1, 2007;
97(2):
1553 - 1565.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. J. Brouwer and R. van Ee
Visual Cortex Allows Prediction of Perceptual States during Ambiguous Structure-From-Motion
J. Neurosci.,
January 31, 2007;
27(5):
1015 - 1023.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Sterzer and A. Kleinschmidt
A neural basis for inference in perceptual ambiguity
PNAS,
January 2, 2007;
104(1):
323 - 328.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Nienborg and B. G. Cumming
Macaque v2 neurons, but not v1 neurons, show choice-related activity.
J. Neurosci.,
September 13, 2006;
26(37):
9567 - 9578.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Liu and W. T. Newsome
Local field potential in cortical area MT: stimulus tuning and behavioral correlations.
J. Neurosci.,
July 26, 2006;
26(30):
7779 - 7790.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Sapir, G. d'Avossa, M. McAvoy, G. L. Shulman, and M. Corbetta
Brain signals for spatial attention predict performance in a motion discrimination task
PNAS,
December 6, 2005;
102(49):
17810 - 17815.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Uka, S. Tanabe, M. Watanabe, and I. Fujita
Neural Correlates of Fine Depth Discrimination in Monkey Inferior Temporal Cortex
J. Neurosci.,
November 16, 2005;
25(46):
10796 - 10802.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Tanabe, T. Doi, K. Umeda, and I. Fujita
Disparity-Tuning Characteristics of Neuronal Responses to Dynamic Random-Dot Stereograms in Macaque Visual Area V4
J Neurophysiol,
October 1, 2005;
94(4):
2683 - 2699.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Krekelberg and T. D. Albright
Motion Mechanisms in Macaque MT
J Neurophysiol,
May 1, 2005;
93(5):
2908 - 2921.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. J. DiCarlo and J. H. R. Maunsell
Using Neuronal Latency to Determine Sensory-Motor Processing Pathways in Reaction Time Tasks
J Neurophysiol,
May 1, 2005;
93(5):
2974 - 2986.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Pessoa and S. Padmala
Quantitative prediction of perceptual decisions during near-threshold fear detection
PNAS,
April 12, 2005;
102(15):
5612 - 5617.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Liu and W. T. Newsome
Correlation between Speed Perception and Neural Activity in the Middle Temporal Visual Area
J. Neurosci.,
January 19, 2005;
25(3):
711 - 722.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Tanabe, K. Umeda, and I. Fujita
Rejection of False Matches for Binocular Correspondence in Macaque Visual Cortical Area V4
J. Neurosci.,
September 15, 2004;
24(37):
8170 - 8180.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Krug, B. G. Cumming, and A. J. Parker
Comparing Perceptual Signals of Single V5/MT Neurons in Two Binocular Depth Tasks
J Neurophysiol,
September 1, 2004;
92(3):
1586 - 1596.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. W. Heuer and K. H. Britten
Optic Flow Signals in Extrastriate Area MST: Comparison of Perceptual and Neuronal Sensitivity
J Neurophysiol,
March 1, 2004;
91(3):
1314 - 1326.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. D. Nguyenkim and G. C. DeAngelis
Disparity-Based Coding of Three-Dimensional Surface Orientation by Macaque Middle Temporal Neurons
J. Neurosci.,
August 6, 2003;
23(18):
7117 - 7128.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Uka and G. C. DeAngelis
Contribution of Middle Temporal Area to Coarse Depth Discrimination: Comparison of Neuronal and Psychophysical Sensitivity
J. Neurosci.,
April 15, 2003;
23(8):
3515 - 3530.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. C. DeAngelis and T. Uka
Coding of Horizontal Disparity and Velocity by MT Neurons in the Alert Macaque
J Neurophysiol,
February 1, 2003;
89(2):
1094 - 1111.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Liu and W. T. Newsome
Functional Organization of Speed Tuned Neurons in Visual Area MT
J Neurophysiol,
January 1, 2003;
89(1):
246 - 256.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Grunewald, D. C. Bradley, and R. A. Andersen
Neural Correlates of Structure-from-Motion Perception in Macaque V1 and MT
J. Neurosci.,
July 15, 2002;
22(14):
6195 - 6207.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Sugihara, I. Murakami, K. V. Shenoy, R. A. Andersen, and H. Komatsu
Response of MSTd Neurons to Simulated 3D Orientation of Rotating Planes
J Neurophysiol,
January 1, 2002;
87(1):
273 - 285.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
