 |
|||||
|
|||||
|
|||||
|
|||||
|
|||||
Previous Article | Next Article
The Journal of Neuroscience, June 15, 2002, 22(12):5081-5090
Visual and Anticipatory Bias in Three Cortical Eye Fields of the Monkey during an Adaptive Decision-Making Task
Brian Coe, Kazuya Tomihara, Masako Matsuzawa, and Okihide Hikosaka Department of Physiology, School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-Ku, Tokyo 113, Japan
To examine the role of three cortical eye fields during internally guided decision-making processes, we recorded neuronal activities in the frontal eye field (FEF), supplementary eye field (SEF), and lateral intraparietal cortex (LIP) using a free-choice delayed saccade task with two synchronized targets. Although the monkeys must perform the task in a time-locked manner, they were free to choose either the receptive field (RF) target or the nonreceptive field (nRF) target to receive reward. In all three areas we found neurons with stronger activation during trials when the monkey was going to make a saccade to the RF target (RF trials) than to the nRF target (nRF trials). Modulation occurred not only during target presentation (visual bias) but also before target presentation (anticipatory bias). The visual bias was evident as an attenuated visual response to the RF stimulus in nRF trials. The anticipatory bias, however, was seen as an enhancement of pretarget activity in the RF trials. We analyzed the activity during the 500 msec before target presentation and found that 22.5% of FEF and 31.3% of LIP neurons and 49.1% of SEF neurons showed higher activity during the RF trials. To more accurately determine when each neuron started to show preferential activity, we used a new inverse interspike interval analysis procedure. Our results suggest that although all three cortical eye fields reflect attentional and intentional aspects of sensorimotor processing, SEF plays an earlier and perhaps more cognitive role in internally guided decision-making processes for saccades.
Key words: frontal eye fields; supplementary eye fields; lateral intraparietal cortex; single-cell activity; attention; intention; decision making; free-choice task; saccade
Copyright © 2002 Society for Neuroscience 0270-6474/02/22125081-10$05.00/0
This article has been cited by other articles:
S. J. Gershman, B. Pesaran, and N. D. Daw
Human Reinforcement Learning Subdivides Structured Action Spaces by Learning Effector-Specific Values
J. Neurosci., October 28, 2009; 29(43): 13524 - 13531.
[Abstract] [Full Text] [PDF]
S. V. Shepherd, J. T. Klein, R. O. Deaner, and M. L. Platt
Mirroring of attention by neurons in macaque parietal cortex
PNAS, June 9, 2009; 106(23): 9489 - 9494.
[Abstract] [Full Text] [PDF]
H. Seo, D. J. Barraclough, and D. Lee
Lateral Intraparietal Cortex and Reinforcement Learning during a Mixed-Strategy Game
J. Neurosci., June 3, 2009; 29(22): 7278 - 7289.
[Abstract] [Full Text] [PDF]
D. Thevarajah, A. Mikulic, and M. C. Dorris
Role of the Superior Colliculus in Choosing Mixed-Strategy Saccades
J. Neurosci., February 18, 2009; 29(7): 1998 - 2008.
[Abstract] [Full Text] [PDF]
D. B. Liston and L. S. Stone
Effects of Prior Information and Reward on Oculomotor and Perceptual Choices
J. Neurosci., December 17, 2008; 28(51): 13866 - 13875.
[Abstract] [Full Text] [PDF]
A. Mohanty, D. R. Gitelman, D. M. Small, and M. M. Mesulam
The Spatial Attention Network Interacts with Limbic and Monoaminergic Systems to Modulate Motivation-Induced Attention Shifts
Cereb Cortex, November 1, 2008; 18(11): 2604 - 2613.
[Abstract] [Full Text] [PDF]
A. Mikulic and M. C. Dorris
Temporal and Spatial Allocation of Motor Preparation During a Mixed-Strategy Game
J Neurophysiol, October 1, 2008; 100(4): 2101 - 2108.
[Abstract] [Full Text] [PDF]
R. Ackerley, K. Wild, and A. Makin
Cognitive Influences on the Generation of Eye Movements
J. Neurosci., September 3, 2008; 28(36): 8863 - 8864.
[Full Text] [PDF]
P. C. J. Taylor, M. F. S. Rushworth, and A. C. Nobre
Choosing Where to Attend and the Medial Frontal Cortex: An fMRI Study
J Neurophysiol, September 1, 2008; 100(3): 1397 - 1406.
[Abstract] [Full Text] [PDF]
S. Rezvani and B. D. Corneil
Recruitment of a Head-Turning Synergy by Low-Frequency Activity in the Primate Superior Colliculus
J Neurophysiol, July 1, 2008; 100(1): 397 - 411.
[Abstract] [Full Text] [PDF]
U. Ettinger, D. H. ffytche, V. Kumari, N. Kathmann, B. Reuter, F. Zelaya, and S. C. R. Williams
Decomposing the Neural Correlates of Antisaccade Eye Movements Using Event-Related fMRI
Cereb Cortex, May 1, 2008; 18(5): 1148 - 1159.
[Abstract] [Full Text] [PDF]
C. de Hemptinne, P. Lefevre, and M. Missal
Neuronal Bases of Directional Expectation and Anticipatory Pursuit
J. Neurosci., April 23, 2008; 28(17): 4298 - 4310.
[Abstract] [Full Text] [PDF]
T. A. Kelley, J. T. Serences, B. Giesbrecht, and S. Yantis
Cortical Mechanisms for Shifting and Holding Visuospatial Attention
Cereb Cortex, January 1, 2008; 18(1): 114 - 125.
[Abstract] [Full Text] [PDF]
Y. Uchida, X. Lu, S. Ohmae, T. Takahashi, and S. Kitazawa
Neuronal Activity Related to Reward Size and Rewarded Target Position in Primate Supplementary Eye Field
J. Neurosci., December 12, 2007; 27(50): 13750 - 13755.
[Abstract] [Full Text] [PDF]
T. Ikeda and O. Hikosaka
Positive and Negative Modulation of Motor Response in Primate Superior Colliculus by Reward Expectation
J Neurophysiol, December 1, 2007; 98(6): 3163 - 3170.
[Abstract] [Full Text] [PDF]
P. Cisek
Cortical mechanisms of action selection: the affordance competition hypothesis
Phil Trans R Soc B, September 29, 2007; 362(1485): 1585 - 1599.
[Abstract] [Full Text] [PDF]
D. E. Moorman and C. R. Olson
Combination of Neuronal Signals Representing Object-Centered Location and Saccade Direction in Macaque Supplementary Eye Field
J Neurophysiol, May 1, 2007; 97(5): 3554 - 3566.
[Abstract] [Full Text] [PDF]
D. E. Moorman and C. R. Olson
Impact of Experience on the Representation of Object-Centered Space in the Macaque Supplementary Eye Field
J Neurophysiol, March 1, 2007; 97(3): 2159 - 2173.
[Abstract] [Full Text] [PDF]
H. Scherberger and R. A. Andersen
Target Selection Signals for Arm Reaching in the Posterior Parietal Cortex
J. Neurosci., February 21, 2007; 27(8): 2001 - 2012.
[Abstract] [Full Text] [PDF]
L. Ding and O. Hikosaka
Temporal Development of Asymmetric Reward-Induced Bias in Macaques
J Neurophysiol, January 1, 2007; 97(1): 57 - 61.
[Abstract] [Full Text] [PDF]
E. Procyk and P. S Goldman-Rakic
Modulation of Dorsolateral Prefrontal Delay Activity during Self-Organized Behavior.
J. Neurosci., November 1, 2006; 26(44): 11313 - 11323.
[Abstract] [Full Text] [PDF]
P. Cisek
Integrated neural processes for defining potential actions and deciding between them: a computational model.
J. Neurosci., September 20, 2006; 26(38): 9761 - 9770.
[Abstract] [Full Text] [PDF]
B. M. Lawrence and L. H. Snyder
Comparison of Effector-Specific Signals in Frontal and Parietal Cortices
J Neurophysiol, September 1, 2006; 96(3): 1393 - 1400.
[Abstract] [Full Text] [PDF]
L. Ding and O. Hikosaka
Comparison of reward modulation in the frontal eye field and caudate of the macaque.
J. Neurosci., June 21, 2006; 26(25): 6695 - 6703.
[Abstract] [Full Text] [PDF]
C. Hamel-Paquet, L. E. Sergio, and J. F. Kalaska
Parietal Area 5 Activity Does Not Reflect the Differential Time-Course of Motor Output Kinetics During Arm-Reaching and Isometric-Force Tasks
J Neurophysiol, June 1, 2006; 95(6): 3353 - 3370.
[Abstract] [Full Text] [PDF]
J. W. Bisley and M. E. Goldberg
Neural Correlates of Attention and Distractibility in the Lateral Intraparietal Area
J Neurophysiol, March 1, 2006; 95(3): 1696 - 1717.
[Abstract] [Full Text] [PDF]
K. Samejima, Y. Ueda, K. Doya, and M. Kimura
Representation of Action-Specific Reward Values in the Striatum
Science, November 25, 2005; 310(5752): 1337 - 1340.
[Abstract] [Full Text] [PDF]
K. Watanabe and O. Hikosaka
Immediate Changes in Anticipatory Activity of Caudate Neurons Associated With Reversal of Position-Reward Contingency
J Neurophysiol, September 1, 2005; 94(3): 1879 - 1887.
[Abstract] [Full Text] [PDF]
M. R. Roesch and C. R. Olson
Neuronal Activity Dependent on Anticipated and Elapsed Delay in Macaque Prefrontal Cortex, Frontal and Supplementary Eye Fields, and Premotor Cortex
J Neurophysiol, August 1, 2005; 94(2): 1469 - 1497.
[Abstract] [Full Text] [PDF]
R. J. Krauzlis
The Control of Voluntary Eye Movements: New Perspectives
Neuroscientist, April 1, 2005; 11(2): 124 - 137.
[Abstract] [PDF]
P. W. Glimcher and A. Rustichini
Neuroeconomics: The Consilience of Brain and Decision
Science, October 15, 2004; 306(5695): 447 - 452.
[Abstract] [Full Text] [PDF]
M. Missal and S. J. Heinen
Supplementary Eye Fields Stimulation Facilitates Anticipatory Pursuit
J Neurophysiol, August 1, 2004; 92(2): 1257 - 1262.
[Abstract] [Full Text] [PDF]
M. Isoda and J. Tanji
Participation of the Primate Presupplementary Motor Area in Sequencing Multiple Saccades
J Neurophysiol, July 1, 2004; 92(1): 653 - 659.
[Abstract] [Full Text] [PDF]
J. Fukushima, T. Akao, N. Takeichi, S. Kurkin, C. R. S. Kaneko, and K. Fukushima
Pursuit-Related Neurons in the Supplementary Eye Fields: Discharge During Pursuit and Passive Whole Body Rotation
J Neurophysiol, June 1, 2004; 91(6): 2809 - 2825.
[Abstract] [Full Text] [PDF]
N. Amador, M. Schlag-Rey, and J. Schlag
Primate Antisaccade. II. Supplementary Eye Field Neuronal Activity Predicts Correct Performance
J Neurophysiol, April 1, 2004; 91(4): 1672 - 1689.
[Abstract] [Full Text] [PDF]
R. J. Leigh and C. Kennard
Using saccades as a research tool in the clinical neurosciences
Brain, March 1, 2004; 127(3): 460 - 477.
[Abstract] [Full Text] [PDF]
M. Isoda and J. Tanji
Contrasting Neuronal Activity in the Supplementary and Frontal Eye Fields During Temporal Organization of Multiple Saccades
J Neurophysiol, November 1, 2003; 90(5): 3054 - 3065.
[Abstract] [Full Text] [PDF]
J. C. Martinez-Trujillo, E. M. Klier, H. Wang, and J. D. Crawford
Contribution of Head Movement to Gaze Command Coding in Monkey Frontal Cortex and Superior Colliculus
J Neurophysiol, October 1, 2003; 90(4): 2770 - 2776.
[Abstract] [Full Text] [PDF]
M. R. Roesch and C. R. Olson
Impact of Expected Reward on Neuronal Activity in Prefrontal Cortex, Frontal and Supplementary Eye Fields and Premotor Cortex
J Neurophysiol, September 1, 2003; 90(3): 1766 - 1789.
[Abstract] [Full Text] [PDF]
J. C. Martinez-Trujillo, H. Wang, and J. D. Crawford
Electrical Stimulation of the Supplementary Eye Fields in the Head-Free Macaque Evokes Kinematically Normal Gaze Shifts
J Neurophysiol, June 1, 2003; 89(6): 2961 - 2974.
[Abstract] [Full Text] [PDF]
H. Scherberger, M. A. Goodale, and R. A. Andersen
Target Selection for Reaching and Saccades Share a Similar Behavioral Reference Frame in the Macaque
J Neurophysiol, March 1, 2003; 89(3): 1456 - 1466.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|