 |
||||
|
||||
|
||||
|
||||
Previous Article | Next Article
The Journal of Neuroscience, July 15, 2002, 22(14):6228-6238
Interneuronal Basis of the Generation of Related but Distinct Motor Programs in Aplysia: Implications for Current Neuronal Models of Vertebrate Intralimb Coordination
Jian Jing and Klaudiusz R. Weiss Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York 10029-6574
Coordination of two sets of movements, protraction-retraction versus opening-closing, of the feeding apparatus (the radula) in ingestive and egestive motor programs of Aplysia resembles vertebrate intralimb coordination in that the relative timing of the two sets of movements differs in the two motor programs. In both ingestion and egestion, radula protraction and retraction alternate, whereas radula closure shifts its phase relative to protraction-retraction. In egestion, the radula closes in protraction; in ingestion, the radula closes in retraction. In both ingestive and egestive motor programs elicited by the command-like neuron, cerebral-buccal interneuron-2 (CBI-2), the protraction and retraction movements are mediated by the same sets of controller interneurons. In contrast, radula closure is mediated by two controller interneurons, B20 and B40, that are preferentially active in egestion and ingestion, respectively. In egestion, B20, active in protraction, drives closure motorneuron B8 in protraction, whereas in ingestion, B40, also active in protraction, uses a functionally novel mechanism, fast inhibition and slow excitation, to drive B8 in retraction. Our findings are summarized in a neural model that permits a conceptual comparison of our model with two previous hypothetical models of intralimb coordination in spinal circuits that were proposed by Grillner (1981, 1985) and Berkowitz and Stein (1994). Although our model supports the existence of separate controllers for different movements as in the Grillner (1981, 1985) model; in terms of basic mechanisms, our model is similar to the Berkowitz and Stein (1994) model because the closure movement is mediated by separate controllers in different programs, and thus both models can be classified as recruitment models.
Key words: Aplysia; feeding; ingestion; egestion; central pattern generator; mollusc; motor program; motor pattern selection; interneuron; intralimb coordination
Copyright © 2002 Society for Neuroscience 0270-6474/02/22146228-11$05.00/0
This article has been cited by other articles:
A. Berkowitz
Physiology and Morphology of Shared and Specialized Spinal Interneurons for Locomotion and Scratching
J Neurophysiol, June 1, 2008; 99(6): 2887 - 2901.
[Abstract] [Full Text] [PDF]
D. Levitan, L. C. Lyons, A. Perelman, C. L. Green, B. Motro, A. Eskin, and A. J. Susswein
Training with inedible food in Aplysia causes expression of C/EBP in the buccal but not cerebral ganglion
Learn. Mem., May 28, 2008; 15(6): 412 - 416.
[Abstract] [Full Text] [PDF]
I. Hurwitz, A. Ophir, A. Korngreen, J. Koester, and A. J. Susswein
Currents Contributing to Decision Making in Neurons B31/B32 of Aplysia
J Neurophysiol, February 1, 2008; 99(2): 814 - 830.
[Abstract] [Full Text] [PDF]
K. Sasaki, M. R. Due, J. Jing, and K. R. Weiss
Feeding CPG in Aplysia Directly Controls Two Distinct Outputs of a Compartmentalized Interneuron That Functions as a CPG Element
J Neurophysiol, December 1, 2007; 98(6): 3796 - 3801.
[Abstract] [Full Text] [PDF]
W.-C. Li, B. Sautois, A. Roberts, and S. R. Soffe
Reconfiguration of a Vertebrate Motor Network: Specific Neuron Recruitment and Context-Dependent Synaptic Plasticity
J. Neurosci., November 7, 2007; 27(45): 12267 - 12276.
[Abstract] [Full Text] [PDF]
J.-s. Wu, M. R. Due, K. Sasaki, A. Proekt, J. Jing, and K. R. Weiss
State Dependence of Spike Timing and Neuronal Function in a Motor Pattern Generating Network
J. Neurosci., October 3, 2007; 27(40): 10818 - 10831.
[Abstract] [Full Text] [PDF]
K. Nishikawa, A. A. Biewener, P. Aerts, A. N. Ahn, H. J. Chiel, M. A. Daley, T. L. Daniel, R. J. Full, M. E. Hale, T. L. Hedrick, et al.
Neuromechanics: an integrative approach for understanding motor control
Integr. Comp. Biol., July 1, 2007; 47(1): 16 - 54.
[Abstract] [Full Text] [PDF]
A. Proekt, J. Jing, and K. R. Weiss
Multiple Contributions of an Input-Representing Neuron to the Dynamics of the Aplysia Feeding Network
J Neurophysiol, April 1, 2007; 97(4): 3046 - 3056.
[Abstract] [Full Text] [PDF]
J. Jing, F. S. Vilim, C. C. Horn, V. Alexeeva, N. G. Hatcher, K. Sasaki, I. Yashina, Y. Zhurov, I. Kupfermann, J. V. Sweedler, et al.
From Hunger to Satiety: Reconfiguration of a Feeding Network by Aplysia Neuropeptide Y
J. Neurosci., March 28, 2007; 27(13): 3490 - 3502.
[Abstract] [Full Text] [PDF]
D. M. Neustadter, R. L. Herman, R. F. Drushel, D. W. Chestek, and H. J. Chiel
The kinematics of multifunctionality: comparisons of biting and swallowing in Aplysia californica
J. Exp. Biol., January 15, 2007; 210(2): 238 - 260.
[Abstract] [Full Text] [PDF]
H. Ye, D. W. Morton, and H. J. Chiel
Neuromechanics of Multifunctionality during Rejection in Aplysia californica.
J. Neurosci., October 18, 2006; 26(42): 10743 - 10755.
[Abstract] [Full Text] [PDF]
M. Diaz-Rios and M. W. Miller
Target-Specific Regulation of Synaptic Efficacy in the Feeding Central Pattern Generator of Aplysia: Potential Substrates for Behavioral Plasticity?
Biol. Bull., June 1, 2006; 210(3): 215 - 229.
[Abstract] [Full Text] [PDF]
T. P. Norekian and A. Y. Malyshev
Neural Mechanisms Underlying Co-Activation of Functionally Antagonistic Motoneurons During a Clione Feeding Behavior
J Neurophysiol, April 1, 2006; 95(4): 2560 - 2569.
[Abstract] [Full Text] [PDF]
H. Ye, D. W. Morton, and H. J. Chiel
Neuromechanics of Coordination during Swallowing in Aplysia californica
J. Neurosci., February 1, 2006; 26(5): 1470 - 1485.
[Abstract] [Full Text] [PDF]
A. Proekt, F. S. Vilim, V. Alexeeva, V. Brezina, A. Friedman, J. Jing, L. Li, Y. Zhurov, J. V. Sweedler, and K. R. Weiss
Identification of a New Neuropeptide Precursor Reveals a Novel Source of Extrinsic Modulation in the Feeding System of Aplysia
J. Neurosci., October 19, 2005; 25(42): 9637 - 9648.
[Abstract] [Full Text] [PDF]
C. S. Lum, Y. Zhurov, E. C. Cropper, K. R. Weiss, and V. Brezina
Variability of Swallowing Performance in Intact, Freely Feeding Aplysia
J Neurophysiol, October 1, 2005; 94(4): 2427 - 2446.
[Abstract] [Full Text] [PDF]
Y. Zhurov, K. R. Weiss, and V. Brezina
Tight or Loose Coupling Between Components of the Feeding Neuromusculature of Aplysia?
J Neurophysiol, July 1, 2005; 94(1): 531 - 549.
[Abstract] [Full Text] [PDF]
M. Diaz-Rios and M. W. Miller
Rapid Dopaminergic Signaling by Interneurons That Contain Markers for Catecholamines and GABA in the Feeding Circuitry of Aplysia
J Neurophysiol, April 1, 2005; 93(4): 2142 - 2156.
[Abstract] [Full Text] [PDF]
Y. Zhurov, A. Proekt, K. R. Weiss, and V. Brezina
Changes of Internal State Are Expressed in Coherent Shifts of Neuromuscular Activity in Aplysia Feeding Behavior
J. Neurosci., February 2, 2005; 25(5): 1268 - 1280.
[Abstract] [Full Text] [PDF]
A. N. Shetreat-Klein and E. C. Cropper
Afferent-Induced Changes in Rhythmic Motor Programs in the Feeding Circuitry of Aplysia
J Neurophysiol, October 1, 2004; 92(4): 2312 - 2322.
[Abstract] [Full Text] [PDF]
J. Jing, E. C. Cropper, I. Hurwitz, and K. R. Weiss
The Construction of Movement with Behavior-Specific and Behavior-Independent Modules
J. Neurosci., July 14, 2004; 24(28): 6315 - 6325.
[Abstract] [Full Text] [PDF]
B. Brembs, D. A. Baxter, and J. H. Byrne
Extending In Vitro Conditioning in Aplysia to Analyze Operant and Classical Processes in the Same Preparation
Learn. Mem., July 1, 2004; 11(4): 412 - 420.
[Abstract] [Full Text] [PDF]
A. Proekt, V. Brezina, and K. R. Weiss
Dynamical basis of intentions and expectations in a simple neuronal network
PNAS, June 22, 2004; 101(25): 9447 - 9452.
[Abstract] [Full Text] [PDF]
R. Mozzachiodi, H. A. Lechner, D. A. Baxter, and J. H. Byrne
In Vitro Analog of Classical Conditioning of Feeding Behavior in Aplysia
Learn. Mem., November 1, 2003; 10(6): 478 - 494.
[Abstract] [Full Text] [PDF]
N. C. Dembrow, J. Jing, A. Proekt, A. Romero, F. S. Vilim, E. C. Cropper, and K. R. Weiss
A Newly Identified Buccal Interneuron Initiates and Modulates Feeding Motor Programs in Aplysia
J Neurophysiol, October 1, 2003; 90(4): 2190 - 2204.
[Abstract] [Full Text] [PDF]
Z. Chen and J. B. Travers
Inactivation of amino acid receptors in medullary reticular formation modulates and suppresses ingestion and rejection responses in the awake rat
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2003; 285(1): R68 - R83.
[Abstract] [Full Text] [PDF]
J. Jing, F. S. Vilim, J.-S. Wu, J.-H. Park, and K. R. Weiss
Concerted GABAergic Actions of Aplysia Feeding Interneurons in Motor Program Specification
J. Neurosci., June 15, 2003; 23(12): 5283 - 5294.
[Abstract] [Full Text] [PDF]
C. G. Evans, J. Jing, S. C. Rosen, and E. C. Cropper
Regulation of Spike Initiation and Propagation in an Aplysia Sensory Neuron: Gating-In via Central Depolarization
J. Neurosci., April 1, 2003; 23(7): 2920 - 2931.
[Abstract] [Full Text] [PDF]
A. L. Weaver and S. L. Hooper
Follower Neurons in Lobster (Panulirus interruptus) Pyloric Network Regulate Pacemaker Period in Complementary Ways
J Neurophysiol, March 1, 2003; 89(3): 1327 - 1338.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|