The Journal of Neuroscience, February 15, 2003, 23(4):1a
CORRECTION
In the article "KIF Dynamics and Regulation of
NR2B Trafficking in Hippocampal Neurons," by Laurent Guillaud,
Mitsutoshi Setou, and Nobutaka Hirokawa, which appeared on pages
131-140 of the January 1, 2003 issue, the authors stated in the third paragraph of the Discussion that the packets studied by Washbourne et
al. [Washbourne P, Bennett JE, McAllister AK (2002) Rapid recruitment of NMDA receptor transport packets to nascent synapses. Nat Neurosci 5:751-759] move at 0.7 mm/sec. In fact, the velocity found by Washbourne et al. concerning the movement of NR1 subunits was 0.07 mm/sec, much slower than the velocity found in this study for the
movememt of KIF17 and the NR2B subunits (0.76 mm/sec). Although both
studies reveal a fast and active transport of the NMDAR subunits, the
difference observed may be the result of the different type of neurons
used (cortical neurons for NR1 and hippocampal neurons for NR2B) and/or
the developmental stage of the neuronal cultures. Guillaud et al.
believe that they are probably monitoring the movement of different
pools of NMDAR packets than the ones reported by Washbourne et al.
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