QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

The Journal of Neuroscience, November 10, 2004, 24(45):10223-10228; doi:10.1523/JNEUROSCI.3373-04.2004

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (23) Citing Articles via Google Scholar Google Scholar Articles by Goh, J. O. S. Articles by Chee, M. W. L. Search for Related Content PubMed PubMed Citation Articles by Goh, J. O. S. Articles by Chee, M. W. L.

 Previous Article  |  Next Article 

Behavioral/Systems/Cognitive
Cortical Areas Involved in Object, Background, and Object-Background Processing Revealed with Functional Magnetic Resonance Adaptation

Joshua O. S. Goh,¹ Soon Chun Siong,¹ Denise Park,² Angela Gutchess,² Andy Hebrank,² and Michael W. L. Chee¹

¹Cognitive Neuroscience Laboratory, SingHealth Research Laboratories, Singapore 169611, Singapore, and ²Beckman Institute, University of Illinois, Urbana-Champaign, Illinois 61801

Previous work has suggested that object and place processing are neuroanatomically dissociated in ventral visual areas under conditions of passive viewing. It has also been shown that the hippocampus and parahippocampal gyrus mediate the integration of objects with background scenes in functional imaging studies, but only when encoding or retrieval processes have been directed toward the relevant stimuli. Using functional magnetic resonance adaptation, we demonstrated that object, background scene, and contextual integration of selectively repeated objects and background scenes could be dissociated during the passive viewing of naturalistic pictures involving object-scene pairings. Specifically, bilateral fusiform areas showed adaptation to object repetition, regardless of whether the associated scene was novel or repeated, suggesting sensitivity to object processing. Bilateral parahippocampal regions showed adaptation to background scene repetition, regardless of whether the focal object was novel or repeated, suggesting selectivity for background scene processing. Finally, bilateral parahippocampal regions distinct from those involved in scene processing and the right hippocampus showed adaptation only when the unique pairing of object with background scene was repeated, suggesting that these regions perform binding operations.

Key words: object processing; scene processing; binding; fMR-A; hippocampus; parahippocampal region

---

Received Aug 17, 2004; revised October 4, 2004; accepted October 4, 2004.

This article has been cited by other articles:

				M. Bar, E. Aminoff, and A. Ishai Famous Faces Activate Contextual Associations in the Parahippocampal Cortex Cereb Cortex, June 1, 2008; 18(6): 1233 - 1238. [Abstract] [Full Text] [PDF]

				W. L. Miller, V. Maffei, G. Bosco, M. Iosa, M. Zago, E. Macaluso, and F. Lacquaniti Vestibular Nuclei and Cerebellum Put Visual Gravitational Motion in Context J Neurophysiol, April 1, 2008; 99(4): 1969 - 1982. [Abstract] [Full Text] [PDF]

				N. Gronau, M. Neta, and M. Bar Integrated contextual representation for objects' identities and their locations. J. Cogn. Neurosci., March 1, 2008; 20(3): 371 - 388. [Abstract] [Full Text] [PDF]

				J. D. Johnson and M. D. Rugg Recollection and the Reinstatement of Encoding-Related Cortical Activity Cereb Cortex, November 1, 2007; 17(11): 2507 - 2515. [Abstract] [Full Text] [PDF]

				S. P. MacEvoy and R. A. Epstein Position Selectivity in Scene- and Object-Responsive Occipitotemporal Regions J Neurophysiol, October 1, 2007; 98(4): 2089 - 2098. [Abstract] [Full Text] [PDF]

				E Aminoff, N Gronau, and M Bar The Parahippocampal Cortex Mediates Spatial and Nonspatial Associations Cereb Cortex, July 1, 2007; 17(7): 1493 - 1503. [Abstract] [Full Text] [PDF]

				R. A. Epstein, W. E. Parker, and A. M. Feiler Where Am I Now? Distinct Roles for Parahippocampal and Retrosplenial Cortices in Place Recognition J. Neurosci., June 6, 2007; 27(23): 6141 - 6149. [Abstract] [Full Text] [PDF]

				S. M. Daselaar, M. S. Fleck, and R. Cabeza Triple Dissociation in the Medial Temporal Lobes: Recollection, Familiarity, and Novelty J Neurophysiol, October 1, 2006; 96(4): 1902 - 1911. [Abstract] [Full Text] [PDF]

				M. W. L. Chee, J. O. S. Goh, V. Venkatraman, J. Chow Tan, A. Gutchess, B. Sutton, A. Hebrank, E. Leshikar, and D. Park Age-related changes in object processing and contextual binding revealed using fMR adaptation. J. Cogn. Neurosci., April 1, 2006; 18(4): 495 - 507. [Abstract] [Full Text] [PDF]

				V. Venkatraman, S. C. Siong, M. W. L. Chee, and D. Ansari Effect of Language Switching on Arithmetic: A Bilingual fMRI Study J. Cogn. Neurosci., January 1, 2006; 18(1): 64 - 74. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help