 |
||||
|
||||
|
||||
|
||||
The Journal of Neuroscience, January 19, 2005, 25(3):711-722; doi:10.1523/JNEUROSCI.4034-04.2005
Previous Article | Next Article
Behavioral/Systems/Cognitive
Correlation between Speed Perception and Neural Activity in the Middle Temporal Visual Area
Jing Liu andWilliam T. Newsome Howard Hughes Medical Institute and Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305-5125
We conducted electrophysiological recording and microstimulation experiments to test the hypothesis that the middle temporal visual area (MT) plays a direct role in perception of the speed of moving visual stimuli. We trained rhesus monkeys on a speed discrimination task in which monkeys chose the faster speed of two moving random dot patterns presented simultaneously in spatially segregated apertures. In electrophysiological experiments, we analyzed the activity of speed-tuned MT neurons and multiunit clusters during the discrimination task. Neural activity was correlated with the monkeys' behavioral choices on a trial-to-trial basis (choice probability), and the correlation was predicted by the speed-tuning properties of each unit. In microstimulation experiments, we activated clusters of MT neurons with homogeneous speed-tuning properties during the same speed discrimination task. In one monkey, microstimulation biased speed judgments toward the preferred speed of the stimulated neurons. Together, evidence from these two experiments suggests that MT neurons play a direct role in the perception of visual speed. Comparison of psychometric and neurometric thresholds revealed that single and multineuronal signals were, on average, considerably less sensitive than were the monkeys perceptually, suggesting that signals must be pooled across neurons to account for performance.
Key words: MT; speed; choice probability; microstimulation; neurometric threshold; training effects
Received July 19, 2004; revised December 1, 2004; accepted December 1, 2004.
This article has been cited by other articles:
Y. Yang, J. Zhang, Z. Liang, G. Li, Y. Wang, Y. Ma, Y. Zhou, and A. G. Leventhal
Aging Affects the Neural Representation of Speed in Macaque Area MT
Cereb Cortex, November 26, 2008; (2008) bhn221v1.
[Abstract] [Full Text] [PDF]
D. I. Braun, N. Mennie, C. Rasche, A. C. Schutz, M. J. Hawken, and K. R. Gegenfurtner
Smooth Pursuit Eye Movements to Isoluminant Targets
J Neurophysiol, September 1, 2008; 100(3): 1287 - 1300.
[Abstract] [Full Text] [PDF]
D. J. McKeefry, M. P. Burton, C. Vakrou, B. T. Barrett, and A. B. Morland
Induced Deficits in Speed Perception by Transcranial Magnetic Stimulation of Human Cortical Areas V5/MT+ and V3A
J. Neurosci., July 2, 2008; 28(27): 6848 - 6857.
[Abstract] [Full Text] [PDF]
K. Kawasaki and D. L. Sheinberg
Learning to Recognize Visual Objects With Microstimulation in Inferior Temporal Cortex
J Neurophysiol, July 1, 2008; 100(1): 197 - 211.
[Abstract] [Full Text] [PDF]
K. M. M. Walker, B. Ahmed, and J. W. H. Schnupp
Linking cortical spike pattern codes to auditory perception.
J. Cogn. Neurosci., January 1, 2008; 20(1): 135 - 152.
[Abstract] [Full Text] [PDF]
G. A. Orban
Higher Order Visual Processing in Macaque Extrastriate Cortex
Physiol Rev, January 1, 2008; 88(1): 59 - 89.
[Abstract] [Full Text] [PDF]
J. N. Yang, N. M. Szeverenyi, and D. Ts'o
Neural Resources Associated with Perceptual Judgment across Sensory Modalities
Cereb Cortex, January 1, 2008; 18(1): 38 - 45.
[Abstract] [Full Text] [PDF]
M. A. Hietanen, N. A. Crowder, N. S. C. Price, and M. R. Ibbotson
Influence of adapting speed on speed and contrast coding in the primary visual cortex of the cat
J. Physiol., October 15, 2007; 584(2): 451 - 462.
[Abstract] [Full Text] [PDF]
A. Schlack, B. Krekelberg, and T. D. Albright
Recent History of Stimulus Speeds Affects the Speed Tuning of Neurons in Area MT
J. Neurosci., October 10, 2007; 27(41): 11009 - 11018.
[Abstract] [Full Text] [PDF]
S. R. Allred and B. Jagadeesh
Quantitative Comparison Between Neural Response in Macaque Inferotemporal Cortex and Behavioral Discrimination of Photographic Images
J Neurophysiol, September 1, 2007; 98(3): 1263 - 1277.
[Abstract] [Full Text] [PDF]
S. J. Heinen
Oculomotor Hide and Seek: Pursuing an Accelerating Target Behind an Occluder. Focus on "Target Acceleration Can Be Extracted and Represented Within the Predictive Drive to Ocular Pursuit"
J Neurophysiol, September 1, 2007; 98(3): 1073 - 1074.
[Full Text] [PDF]
C. Palmer, S.-Y. Cheng, and E. Seidemann
Linking Neuronal and Behavioral Performance in a Reaction-Time Visual Detection Task
J. Neurosci., July 25, 2007; 27(30): 8122 - 8137.
[Abstract] [Full Text] [PDF]
R. E. B. Mruczek and D. L. Sheinberg
Activity of Inferior Temporal Cortical Neurons Predicts Recognition Choice Behavior and Recognition Time during Visual Search
J. Neurosci., March 14, 2007; 27(11): 2825 - 2836.
[Abstract] [Full Text] [PDF]
L. C. Osborne, S. S. Hohl, W. Bialek, and S. G. Lisberger
Time Course of Precision in Smooth-Pursuit Eye Movements of Monkeys
J. Neurosci., March 14, 2007; 27(11): 2987 - 2998.
[Abstract] [Full Text] [PDF]
B. S. Webb, T. Ledgeway, and P. V. McGraw
Cortical pooling algorithms for judging global motion direction
PNAS, February 27, 2007; 104(9): 3532 - 3537.
[Abstract] [Full Text] [PDF]
B. Krekelberg, R. J. A. van Wezel, and T. D. Albright
Interactions between Speed and Contrast Tuning in the Middle Temporal Area: Implications for the Neural Code for Speed.
J. Neurosci., August 30, 2006; 26(35): 8988 - 8998.
[Abstract] [Full Text] [PDF]
J. Liu and W. T. Newsome
Local field potential in cortical area MT: stimulus tuning and behavioral correlations.
J. Neurosci., July 26, 2006; 26(30): 7779 - 7790.
[Abstract] [Full Text] [PDF]
B. Krekelberg, R. J. A. van Wezel, and T. D. Albright
Adaptation in Macaque MT Reduces Perceived Speed and Improves Speed Discrimination
J Neurophysiol, January 1, 2006; 95(1): 255 - 270.
[Abstract] [Full Text] [PDF]
H. Nover, C. H. Anderson, and G. C. DeAngelis
A Logarithmic, Scale-Invariant Representation of Speed in Macaque Middle Temporal Area Accounts for Speed Discrimination Performance
J. Neurosci., October 26, 2005; 25(43): 10049 - 10060.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|