QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

The Journal of Neuroscience, August 20, 2008, 28(34):8553-8559; doi:10.1523/JNEUROSCI.2182-08.2008

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Related articles in J. Neurosci. Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (1) Citing Articles via Google Scholar Google Scholar Articles by Priebe, N. J. Search for Related Content PubMed PubMed Citation Articles by Priebe, N. J.

 Previous Article  |  Next Article 

Brief Communications
The Relationship between Subthreshold and Suprathreshold Ocular Dominance in Cat Primary Visual Cortex

Nicholas J. Priebe

Section of Neurobiology, School of Biological Sciences, University of Texas at Austin, Austin, Texas 78705

Correspondence should be addressed to Nicholas J. Priebe, Section of Neurobiology, University of Texas at Austin, 2400 Speedway, Austin, TX 78705. Email: nicholas{at}mail.utexas.edu

Primary visual cortex (V1) is the site at which right and left eye pathways are first integrated, leading to a representation of the visual world in depth. The ocular dominance (OD) of individual cortical neurons varies and may be changed by altering visual experience during the developmental critical period. Estimates of OD, commonly used to quantify the right and left eye synaptic inputs, have previously been based on spike rate. Membrane potential (V_m), however, is more closely related to the synaptic inputs onto neurons and should therefore more closely reflect the degree of input from the two eyes. To determine the relationship between OD based on membrane potential and on spike rate, intracellular recordings were made from visual cortical neurons. OD based on spike rate was systematically more monocular than OD based on membrane potential. The discrepancy between membrane-potential OD and spike-rate OD may be accounted for by a simple model of V_m-to-spike-rate transformation.

Key words: primary visual cortex; spike threshold nonlinearity; intracellular recording; ocular dominance; vision; binocular

---

Received May 13, 2008; revised July 11, 2008; accepted July 12, 2008.

Correspondence should be addressed to Nicholas J. Priebe, Section of Neurobiology, University of Texas at Austin, 2400 Speedway, Austin, TX 78705. Email: nicholas{at}mail.utexas.edu

Related articles in J. Neurosci.:

This Week in The Journal

J. Neurosci. 2008 28: i. [Full Text]  

This article has been cited by other articles:

				J. X. Gittelman, N. Li, and G. D. Pollak Mechanisms Underlying Directional Selectivity for Frequency-Modulated Sweeps in the Inferior Colliculus Revealed by In Vivo Whole-Cell Recordings J. Neurosci., October 14, 2009; 29(41): 13030 - 13041. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help