QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (46) Citing Articles via Google Scholar Google Scholar Articles by Katz, M. J. Search for Related Content PubMed PubMed Citation Articles by Katz, M. J.

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 5, 589-595, Copyright © 1985 by Society for Neuroscience

ARTICLE

How straight do axons grow?

MJ Katz

Detailed growth paths of embryonic frog and chick axons were measured as the axons elongated in dispersed cultures on acid-rinsed glass surfaces. Mathematical analyses demonstrate that, under these conditions, axons do not grow randomly but tend to grow straight. Growth cones appear to actively alternate sides--right and left from the straight line of growth--and the growth cone neck exhibits all possible angles, but the axon itself maintains a fairly constant orientation. It appears that an axonal resistance to bending may be the cause of the intrinsic tendency for relatively straight axonal growth. The natural straightness of axonal growth may be an important developmental determinant of certain in vivo axon patterns.

This article has been cited by other articles:

				J. Xu, W. J. Rosoff, J. S. Urbach, and G. J. Goodhill Adaptation is not required to explain the long-term response of axons to molecular gradients Development, October 15, 2005; 132(20): 4545 - 4552. [Abstract] [Full Text] [PDF]

				G. L. Andrews and G. S. Mastick R-Cadherin Is a Pax6-Regulated, Growth-Promoting Cue for Pioneer Axons J. Neurosci., October 29, 2003; 23(30): 9873 - 9880. [Abstract] [Full Text] [PDF]

				A. J. Jacobs, G. P. Swain, J. A. Snedeker, D. S. Pijak, L. J. Gladstone, and M. E. Selzer Recovery of Neurofilament Expression Selectively in Regenerating Reticulospinal Neurons J. Neurosci., July 1, 1997; 17(13): 5206 - 5220. [Abstract] [Full Text] [PDF]

				P Clark, S Britland, and P Connolly Growth cone guidance and neuron morphology on micropatterned laminin surfaces J. Cell Sci., January 5, 1993; 105(1): 203 - 212. [Abstract] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help