WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience Introducing ALZET?ew Model 2006 Pump
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yuan, B.
Right arrow Articles by Casey, K. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yuan, B.
Right arrow Articles by Casey, K. L.

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 6, 3611-3617, Copyright © 1986 by Society for Neuroscience

ARTICLE

Corticofugal influences of S1 cortex on ventrobasal thalamic neurons in the awake rat

B Yuan, TJ Morrow and KL Casey

Corticofugal influences on the responses of 39 ventrobasal (VB) thalamic neurons to repetitive stimuli were studied in awake rats by focally suppressing the evoked and spontaneous electrocortical activity of the primary (S1) somatosensory cortex with magnesium or lidocaine plus magnesium. Suppression of the S1 cortex reduced the number of spikes discharged by 19 (66%) of 29 VB units in response to each of 25 electrical stimuli delivered to the medial lemniscus; 9 units were unaffected and 1 showed an increased response to 1-10 Hz stimuli. The responses of 6 (38%) of 16 VB units to electrical somatic stimuli were also reduced following S1 cortical suppression; 9 units were unaffected and 1 showed an increased response to 20-40 Hz stimuli. A comparison of the reduced responsiveness of 5 units studied during medial lemniscal and somatic stimulation did not reveal any additional response attenuation attributable to subthalamic corticofugal influences. We conclude that, in the awake rat, somatosensory transmission to VB thalamic neurons is primarily facilitated by S1 corticothalamic neurons.


This article has been cited by other articles:


Home page
 Cereb CortexHome page
V. Khatri and D. J. Simons
Angularly Nonspecific Response Suppression in Rat Barrel Cortex
Cereb Cortex, March 1, 2007; 17(3): 599 - 609.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
L. Li and F. F. Ebner
Cortical Modulation of Spatial and Angular Tuning Maps in the Rat Thalamus
J. Neurosci., January 3, 2007; 27(1): 167 - 179.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
L. Monconduit, A. Lopez-Avila, J.-L. Molat, M. Chalus, and L. Villanueva
Corticofugal Output from the Primary Somatosensory Cortex Selectively Modulates Innocuous and Noxious Inputs in the Rat Spinothalamic System.
J. Neurosci., August 15, 2006; 26(33): 8441 - 8450.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
V. Khatri, J. A. Hartings, and D. J. Simons
Adaptation in Thalamic Barreloid and Cortical Barrel Neurons to Periodic Whisker Deflections Varying in Frequency and Velocity
J Neurophysiol, December 1, 2004; 92(6): 3244 - 3254.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
I. Reichova and S. M. Sherman
Somatosensory Corticothalamic Projections: Distinguishing Drivers From Modulators
J Neurophysiol, October 1, 2004; 92(4): 2185 - 2197.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
D. J. Pinto, J. A. Hartings, J. C. Brumberg, and D. J. Simons
Cortical Damping: Analysis of Thalamocortical Response Transformations in Rodent Barrel Cortex
Cereb Cortex, January 1, 2003; 13(1): 33 - 44.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. L. Casey
Forebrain mechanisms of nociception and pain: Analysis through imaging
PNAS, July 6, 1999; 96(14): 7668 - 7674.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
D. J. Krupa, A. A. Ghazanfar, and M. A. L. Nicolelis
Immediate thalamic sensory plasticity depends on corticothalamic feedback
PNAS, July 6, 1999; 96(14): 8200 - 8205.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. A. Hartings and D. J. Simons
Thalamic Relay of Afferent Responses to 1- to 12-Hz Whisker Stimulation in the Rat
J Neurophysiol, August 1, 1998; 80(2): 1016 - 1019.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C.-Q. Kao and D. A. Coulter
Physiology and Pharmacology of Corticothalamic Stimulation-Evoked Responses in Rat Somatosensory Thalamic Neurons In Vitro
J Neurophysiol, May 1, 1997; 77(5): 2661 - 2676.
[Abstract] [Full Text] [PDF]


-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2008 by Society for Neuroscience ONLINE ISSN: 1529-2401
-