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ARTICLE, CELLULAR/MOLECULAR

Protofibrillar Intermediates of Amyloid β-Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons

Dean M. Hartley, Dominic M. Walsh, Chianping P. Ye, Thekla Diehl, Sara Vasquez, Peter M. Vassilev, David B. Teplow and Dennis. J. Selkoe
Journal of Neuroscience 15 October 1999, 19 (20) 8876-8884; DOI: https://doi.org/10.1523/JNEUROSCI.19-20-08876.1999
Dean M. Hartley
Department of Neurology and Medicine,Harvard Medical School, and the
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Dominic M. Walsh
Department of Neurology and Medicine,Harvard Medical School, and the
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Chianping P. Ye
Center forNeurologic Diseases and Division of Endocrinology, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02115
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Thekla Diehl
Department of Neurology and Medicine,Harvard Medical School, and the
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Sara Vasquez
Department of Neurology and Medicine,Harvard Medical School, and the
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Peter M. Vassilev
Center forNeurologic Diseases and Division of Endocrinology, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02115
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David B. Teplow
Department of Neurology and Medicine,Harvard Medical School, and the
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Dennis. J. Selkoe
Department of Neurology and Medicine,Harvard Medical School, and the
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The Journal of Neuroscience: 19 (20)
Journal of Neuroscience
Vol. 19, Issue 20
15 Oct 1999
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Protofibrillar Intermediates of Amyloid β-Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons
Dean M. Hartley, Dominic M. Walsh, Chianping P. Ye, Thekla Diehl, Sara Vasquez, Peter M. Vassilev, David B. Teplow, Dennis. J. Selkoe
Journal of Neuroscience 15 October 1999, 19 (20) 8876-8884; DOI: 10.1523/JNEUROSCI.19-20-08876.1999

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Protofibrillar Intermediates of Amyloid β-Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons
Dean M. Hartley, Dominic M. Walsh, Chianping P. Ye, Thekla Diehl, Sara Vasquez, Peter M. Vassilev, David B. Teplow, Dennis. J. Selkoe
Journal of Neuroscience 15 October 1999, 19 (20) 8876-8884; DOI: 10.1523/JNEUROSCI.19-20-08876.1999
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Keywords

  • Alzheimer
  • amyloid β-protein
  • neurotoxicity
  • electrophysiology
  • fibrillogenesis
  • neurodegeneration

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