Article Information
- Received April 9, 2001
- Revision received July 30, 2001
- Accepted September 5, 2001
- First published November 15, 2001.
- Version of record published November 15, 2001.
Author Information
- Gilles Sansig1,
- Trevor J. Bushell2,
- Vernon R. J. Clarke2,
- Andrei Rozov3,
- Nail Burnashev3,
- Chantal Portet1,
- Fabrizio Gasparini1,
- Markus Schmutz1,
- Klaus Klebs1,
- Ryuichi Shigemoto4,
- Peter J. Flor1,
- Rainer Kuhn1,
- Thomas Knoepfel1,
- Markus Schroeder1,
- David R. Hampson5,
- Valerie J. Collett2,
- Congxiao Zhang6,
- Robert M. Duvoisin6,
- Graham L. Collingridge2, and
- Herman van der Putten1
- 1Nervous System Department, Novartis Pharma AG, CH-4002 Basel, Switzerland,
- 2Medical Research Council Center for Synaptic Plasticity, Department of Anatomy, The School of Medical Sciences, University of Bristol, Bristol, BS8 1TD, United Kingdom,
- 3Abteilung Zellphysiologie, Max-Planck-Institut für Medizinische Forschung, D-69120 Heidelberg, Germany,
- 4Division of Cerebral Structure, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8585, Japan,
- 5Faculty of Pharmacy and Department of Pharmacology, University of Toronto, Ontario, Canada M5S 2S2, and
- 6Margaret M. Dyson Vision Research Institute, Department of Ophthalmology, Cornell University Medical College, New York, New York 10021
Author contributions
Disclosures
- Received April 9, 2001.
- Revision received July 30, 2001.
- Accepted September 5, 2001.
This work was supported in part by the Biotechnology and Biological Sciences Research Council and Medical Research Council (UK). We thank Doris Ruegg for sequencing, Gemma Texido and Klaus Rajewsky for pTV-0 DNA, J.-F. Pin for mGluR8 cDNA, K. von Figura for E14 ES cells, Pedro Grandes for histological examination of brain sections, Christoph Wiessner for help with plots and statistics, Valerie Schuler for help with Western blots, and the team of the Novartis special strain breeding facility for their support.
G.S. and T.J.B. contributed equally to this work.
Correspondence should be addressed to Herman van der Putten, Nervous System Department, Novartis Pharma AG, K125.5.13, CH-4002 Basel, Switzerland. E-mail: p_herman.van_der_putten{at}pharma.novartis.com.
T. Knoepfel's present address: Laboratory for Neuronal Circuit Dynamics, The Institute of Physical and Chemical Research (RIKEN) Brain Science Institute, 2-1 Hirosawa, Wako-Shi, Saitama 351-0198, Japan.
T. Bushell's present address: Imperial College, Department of Biophysics, Prince Consort Road, London SW7 2BW, UK.
C. Zhang's present address: National Eye Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20982-1857.
R. Duvoisin's present address: Neurological Sciences Institute, Oregon Health Sciences University, Portland, OR 97201.
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