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Cellular/Molecular

Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity

Andrey Y. Abramov, Laura Canevari and Michael R. Duchen
Journal of Neuroscience 15 June 2003, 23 (12) 5088-5095
Andrey Y. Abramov
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Laura Canevari
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Michael R. Duchen
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Article Information

PubMed 
12832532
Published By 
Society for Neuroscience
History 
  • Received February 12, 2003
  • Revision received April 4, 2003
  • Accepted April 10, 2003
  • Published in print June 15, 2003.
Copyright & Usage 
Copyright © 2003 Society for Neuroscience 0270-6474/03/235088-08.00/0

Author Information

  1. Andrey Y. Abramov1,
  2. Laura Canevari2, and
  3. Michael R. Duchen1
  1. 1Mitochondrial Biology Group, Department of Physiology, University College London, London WC1E 6BT, United Kingdom, and 2Miriam Marks Division of Neurochemistry, Institute of Neurology, London WC1N 3BG, United Kingdom
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Disclosures

    • Received February 12, 2003.
    • Revision received April 4, 2003.
    • Accepted April 10, 2003.
  • This work was supported by the Wellcome Trust, the Royal Society, and the Miriam Marks Foundation. We thank Drs. Frances Edwards and Anna de Simoni for providing hippocampal explant cultures and Profs. S. Bolsover and J. B. Clark and Drs. R. Dumollard and J. Jacobson for their invaluable discussion and suggestions.

  • Correspondence should be addressed to Michael R. Duchen, Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK. E-mail: m.duchen{at}ucl.ac.uk.

  • Copyright © 2003 Society for Neuroscience 0270-6474/03/235088-08$15.00/0

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The Journal of Neuroscience: 23 (12)
Journal of Neuroscience
Vol. 23, Issue 12
15 Jun 2003
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Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity
Andrey Y. Abramov, Laura Canevari, Michael R. Duchen
Journal of Neuroscience 15 June 2003, 23 (12) 5088-5095

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Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity
Andrey Y. Abramov, Laura Canevari, Michael R. Duchen
Journal of Neuroscience 15 June 2003, 23 (12) 5088-5095
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