The Journal of Neuroscience, February 4, 2004, 24(5)
In the article "Apamin-Sensitive Small Conductance Calcium-Activated Potassium Channels, through their Selective Coupling to Voltage-Gated Calcium Channels, Are Critical Determinants of the Precision, Pace, and Pattern of Action Potential Generation in Rat Subthalamic Nucleus Neurons In Vitro," by Nicholas E. Hallworth, Charles J. Wilson, and Mark D. Bevan, which appeared on pages 7525–7542 of the August 20, 2003 issue, the following corrections should be noted: (1) Dr. Bevan is affiliated with both the first and third institutions listed (1University of Tennessee, Anatomy and Neurobiology, Memphis, Tennessee 38163, and 3Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611-3008). (2) The second sentence of the abstract should read: "To determine how such patterns of activity are regulated by small conductance potassium (SK)/calcium-activated potassium (KCa) channels and voltage-gated calcium (Cav) channels, STN neurons were recorded in the perforated patch configuration in slices [which were prepared from postnatal day 16 (P16)–P30 rats and held at 37°C] and then treated with the SK KCa channel antagonist apamin or the SK KCa channel agonist 1-ethyl-2-benzimidazolinone or the Cav channel antagonists ω-conotoxin GVIA (Cav2.2-selective) or nifedipine (Cav1.2-1.3-selective)." (3) The sentence beginning on line 7 of page 7526 should read "In recent whole-cell patch clamp recording studies of STN neurons, calcium entry via voltage-gated calcium (Cav) channels predominantly activated small conductance potassium (SK)/calcium-activated potassium (KCa) channels, which played a pivotal, largely suppressive role in shaping activity or activated nonspecific cation channels, which augmented activity (Bevan and Wilson, 1999; Beurrier et al., 1999, 2000; Otsuka et al., 2001)." (4) The second sentence of the legend to Figure 10 should read: "A, B, Combined fluorescent and electrical recordings of subthreshold and suprathreshold rebound responses in an STN neuron (inset)." (5) In the Discussion, the sentence starting on line 8 of the third paragraph should read: "Indeed, SK KCa channel or Cav2.2 channel blockade increased firing rates in response to equivalent input but did not disrupt the pattern of driven activity."