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Supplemental data
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- supplemental material - Supplemental Figure 1: Inhibition of calcineurin with FK506 (200 ng/ml) and cyclosporin A (1 �g/ml) does not alter estradiol-induced CREB phosphorylation (F=17.36; **p <_0.01 vs.="vs." no="no" steroid="steroid" fk506="fk506" csa.--="csa.--" end="end" desc="desc" figure-1.gif="figure-1.gif" _--="_--">
- supplemental material - Supplemental Figure 2: LY367385 does not dampen all Gq signaling, as demonstrated by the increase in CREB phosphorylation following application of the muscarinic receptor agonist pilocarpine (1 �M) (F=120.10; **p <_0.01 in="in" comparison="comparison" to="to" baseline="baseline" with="with" without="without" ly367385.--="ly367385.--" end="end" desc="desc" figure-2.gif="figure-2.gif" _--="_--">
- supplemental material - Supplemental Figure 3: The mGluR2/3-induced reduction in L-type calcium channel mediated CREB phosphorylation is mediated through Gi/o and PKA signaling. (A) Pretreatment with Pertussis toxin (500 ng/ml) blocked the APDC-induced attenuation in CREB phosphorylation (F=112.29; **p <_0.01 b="b" inhibition="inhibition" of="of" pka="pka" with="with" rp-camps="rp-camps" _50="_50" m="m" occluded="occluded" the="the" effect="effect" apdc="apdc" on="on" l-type="l-type" calcium="calcium" channel-mediated="channel-mediated" creb="creb" phosphorylation="phosphorylation" f="64.97;" p0.01.--="p0.01.--" end="end" desc="desc" figure-3.gif="figure-3.gif" _--="_--">
- supplemental material - Supplemental Figure 4: Expression of ER? and ER? in hippocampal cultures derived from both male and female rats. (A) Top: Paired, low magnification photomicrographs of ER? (red) and ?-tubulin (green) in cultured hippocampal neurons from female animals. Middle: Higher magnification of ER? and ?-tubulin in neurons derived from both female and male animals. Bottom: Summary of ER? staining. (B) Similar to A, but ER? expression.