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- supplemental material - Figure 1_sup. Brain areas activated when listening in silence. Activations are superimposed on anatomical axial slices of the MNI template provided with SPM2. The clusters represented on the figure are those described in Table 1. Green: Anterior insula/inferior frontal gyrus. Red: Precentral/inferior frontal /middle frontal gyrus. Deep blue: Median cingulate/supplementary motor area. Magenta : sub-cortical areas. Yellow : temporal gyrus. Light blue: parietal
- supplemental material - Figure 2_sup. Brain areas whose activity correlates with the listening-in-silence duration Activations are superimposed on anatomical axial slices of the MNI template provided with SPM2. The clusters represented on the figure are those described in Table 2. A: listening to the left side. B: listening to the right side. Green: Anterior insula/inferior frontal gyrus. Blue: Precentral/inferior frontal gyrus. Red: temporal gyrus, the location of local minima within these areas are represented in yellow.
- supplemental material - Figure 3_sup. Temporal areas activated when listening in silence. Activations are superimposed on anatomical axial slices of the MNI template provided with SPM2. Results are derived from a mixed effect analysis (11 subjects) and the clusters correspond to the contrast �listening-in-silence vs. resting state� calculated from the values of the scan 1 (represented in black-to-green color scale) or of the scan 4 (represented in black-to-red color scale) acquired after each trial. The increase revealed by the contrast �listening-in-silence vs. resting state� (Table 1) could relate to either of two effects: a baseline shift before sound onset and/or an increase of the sound induced response. We have chosen to address this point by studying the trend of the effect across the 4 scans (results presented in Fig 3). In this case, only sound induced response exhibits a positive trend from scan 1 to scan 4. This supplementary figure illustrates an alternative approach separately studying the effects present in scan 1 (according to the hemodynamic response, no sound induced response occurs in this scan) and scan 4 (the baseline shift effect is attenuated in this scan). We can observe a great similarity with the maps reported in Fig 3, i.e. the distinction between areas exhibiting increased activity induced by sound stimulation and increased activity before sound onset.
- supplemental material - Figure 4_sup. Brain areas exhibiting an increase of the listening-in-silence effect from scan 1 to scan 4 (from 0 to 6 seconds after subject�s response). The values of the �increase of sound-induced hemodynamic response� contrast (see Materials and Methods section for detailed definition of the contrasts) are represented in the black-to-red color scale (contrast #2). The values corresponding to the test of the regression (see Table 2 for detailed definition of the analysis) of the activity with the listening-in-silence duration (0, 1.5, 4.5, 7.5 s) are represented in black-to-green color scale (regression). The results are presented in two separated figures because analysis has been performed separately when listening to the right (upper panel A) or the left side (lower panel B). Green voxels correspond to activities related to the baseline shift and red voxels to activities related to sound processing.