Figure 8.
Expression of EGFP in smooth muscle cells in large blood vessels and cells surrounding small blood vessels in brains of heterozygous EGFPapoE mice. A–C, Merged confocal images of EGFP (green) and anti-α-actin (red), a smooth muscle cell marker, were collected from a 5-month-old heterozygous EGFPapoE mouse. A, Small blood vessels in the hippocampus. B, A small blood vessel in the cortex. C, A large blood vessel in the cortex. D, In situ hybridization shows mouse apoE mRNA along the wall of a large blood vessel in the cortex. E, F, Merged confocal images of EGFP (green) and anti-GFAP (red), an astrocyte marker, were collected from a 5-month-old heterozygous EGFPapoE mouse.