Article Information
- Received October 29, 2008
- Revision received January 5, 2009
- Accepted February 8, 2009
- First published March 18, 2009.
- Version of record published March 18, 2009.
Author Information
- Rimante Minkeviciene1,*,
- Sylvain Rheims3,*,
- Marton B. Dobszay5,*,
- Misha Zilberter5,
- Jarmo Hartikainen1,
- Lívia Fülöp6,
- Botond Penke7,
- Yuri Zilberter4,5,
- Tibor Harkany5,8,
- Asla Pitkänen1,2, and
- Heikki Tanila1,2
- 1A. I. Virtanen Institute, University of Kuopio, and
- 2Department of Neurology, Kuopio University Hospital, FIN-70211 Kuopio, Finland,
- 3Faculté de Sciences de Luminy, Aix Marseille Université, and
- 4Institut National de la Santé et de la Recherche Médicale, Institut de Neurobiologie de la Méditerranée U901, F-13000 Marseille, France,
- 5Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, S-17177 Stockholm, Sweden,
- 6Department of Medical Chemistry and
- 7Supramolecular and Nanostructured Materials Research Group of the Hungarian Academy of Science, University of Szeged, H-6720 Szeged, Hungary,
- 8Institute of Medical Sciences, College of Life Sciences & Medicine, University of Aberdeen, Aberdeen, AB25 2ZD, United Kingdom
- Correspondence should be addressed to Dr. Heikki Tanila, Department of Neurobiology, A. I. Virtanen Institute, University of Kuopio, P.O. Box 1627, Neulaniementie 2, FIN-70211 Kuopio, Finland. Heikki.Tanila{at}uku.fi
Author contributions
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↵*R.M., S.R., and M.B.D. contributed equally to this work.
Disclosures
- Received October 29, 2008.
- Revision received January 5, 2009.
- Accepted February 8, 2009.
-
This work was supported by the Finnish Cultural Foundation (R.M.), Northern-Savonia Regional Funds (R.M.), Institut National de la Santé et de la Recherche Médicale (INSERM; Y.Z. is the recipient of a Contrat d'interface between INSERM and Centre Hospitalier Universitaire Necker Paris, France), the Swedish Medical Research Council (T.H.), the EMBO Young Investigator Programme (T.H.), the Alzheimer's Association (T.H.), the Alzheimer's Research Trust UK (T.H.), the European Union Seventh Framework Program (HEALTH-F2-2007-201159; H.T., T.H., Y.Z., B.P., and L.F.), the Academy of Finland (A.P.), and the Sigrid Juselius Foundation (A.P.). We thank Dr. D. Borchelt and J. Jankowsky for APdE9 colony founders and Merja Lukkari for skillful technical assistance in histology.
- Correspondence should be addressed to Dr. Heikki Tanila, Department of Neurobiology, A. I. Virtanen Institute, University of Kuopio, P.O. Box 1627, Neulaniementie 2, FIN-70211 Kuopio, Finland. Heikki.Tanila{at}uku.fi
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