Figure 2. Retinogeniculate projections at P31 in wild-type and EphB1−/− mice. Coronal sections through the dLGN after whole-eye tracing in one eye and either whole eye (a, b) or VT retina (d, e) anterograde tracing from the other eye. a, d, In wild-type mice, the ipsilateral projection (green) forms a patch in the dorsocentral dLGN surrounded by contralateral terminations (red). Late-born VT RGCs project contralaterally to the dorsal tip of the dLGN (d, e, asterisk). b, e, In EphB1−/− mice, an ectopic patch (arrow) arising from the contralateral eye is adjacent to, but segregated from, the reduced ipsilateral patch. VT RGCs project contralaterally to two distinct sites (e): the dorsal tip of the dLGN, corresponding to the “normal” VT contralateral projection (asterisk), and the ectopic patch (arrow). c, f, Schemes depict dLGN termination regions after the anterograde tracing paradigms in wild-type and EphB1−/− mice. D, Dorsal; V, ventral; M, medial; L, lateral.