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Articles, Development/Plasticity/Repair

Metabotropic Glutamate Receptor 1 Mediates the Electrophysiological and Toxic Actions of the Cycad Derivative β-N-Methylamino-l-Alanine on Substantia Nigra Pars Compacta DAergic Neurons

Maria Letizia Cucchiaroni, Maria Teresa Viscomi, Giorgio Bernardi, Marco Molinari, Ezia Guatteo and Nicola B. Mercuri
Journal of Neuroscience 14 April 2010, 30 (15) 5176-5188; DOI: https://doi.org/10.1523/JNEUROSCI.5351-09.2010
Maria Letizia Cucchiaroni
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Maria Teresa Viscomi
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Giorgio Bernardi
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Marco Molinari
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Ezia Guatteo
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Nicola B. Mercuri
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.5351-09.2010
PubMed 
20392940
Published By 
Society for Neuroscience
History 
  • Received October 29, 2009
  • Revision received December 22, 2009
  • Accepted January 8, 2010
  • Published in print April 14, 2010.
Copyright & Usage 
Copyright © 2010 the authors 0270-6474/10/305176-13$15.00/0

Author Information

  1. Maria Letizia Cucchiaroni1,
  2. Maria Teresa Viscomi1,
  3. Giorgio Bernardi1,2,
  4. Marco Molinari1,
  5. Ezia Guatteo1,*, and
  6. Nicola B. Mercuri1,2,*
  1. 1Santa Lucia Foundation Istituto di Ricovero e Cura a Carattere Scientifico, 00143 Rome, Italy, and
  2. 2Department of Neuroscience, University of Rome “Tor Vergata,” 00133 Rome, Italy
  1. Correspondence should be addressed to Prof. Nicola B. Mercuri, Fondazione Santa Lucia, Via del Fosso di Fiorano 64, 00143 Rome, Italy. mercurin{at}med.uniroma2.it
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Author contributions

  1. ↵*E.G. and N.B.M. contributed equally to this work.

View Abstract

Disclosures

    • Received October 29, 2009.
    • Revision received December 22, 2009.
    • Accepted January 8, 2010.
  • The study was supported by grants from the Ministero della Salute (to N.B.M.). We are grateful to Dr. Peter S. Freestone and Prof. Janusz Lipski for their comments on the manuscript.

  • Correspondence should be addressed to Prof. Nicola B. Mercuri, Fondazione Santa Lucia, Via del Fosso di Fiorano 64, 00143 Rome, Italy. mercurin{at}med.uniroma2.it

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The Journal of Neuroscience: 30 (15)
Journal of Neuroscience
Vol. 30, Issue 15
14 Apr 2010
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Metabotropic Glutamate Receptor 1 Mediates the Electrophysiological and Toxic Actions of the Cycad Derivative β-N-Methylamino-l-Alanine on Substantia Nigra Pars Compacta DAergic Neurons
Maria Letizia Cucchiaroni, Maria Teresa Viscomi, Giorgio Bernardi, Marco Molinari, Ezia Guatteo, Nicola B. Mercuri
Journal of Neuroscience 14 April 2010, 30 (15) 5176-5188; DOI: 10.1523/JNEUROSCI.5351-09.2010

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Metabotropic Glutamate Receptor 1 Mediates the Electrophysiological and Toxic Actions of the Cycad Derivative β-N-Methylamino-l-Alanine on Substantia Nigra Pars Compacta DAergic Neurons
Maria Letizia Cucchiaroni, Maria Teresa Viscomi, Giorgio Bernardi, Marco Molinari, Ezia Guatteo, Nicola B. Mercuri
Journal of Neuroscience 14 April 2010, 30 (15) 5176-5188; DOI: 10.1523/JNEUROSCI.5351-09.2010
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