Article Information
- Received March 1, 2010
- Revision received May 5, 2010
- Accepted May 11, 2010
- First published July 7, 2010.
- Version of record published July 7, 2010.
Author Information
- Jan M. Deussing1,
- Johannes Breu1,
- Claudia Kühne1,
- Magdalena Kallnik2,
- Mirjam Bunck1,
- Lisa Glasl2,
- Yi-Chun Yen1,
- Mathias V. Schmidt1,
- Regine Zurmühlen1,
- Annette M. Vogl1,
- Valérie Gailus-Durner3,
- Helmut Fuchs3,
- Sabine M. Hölter2,
- Carsten T. Wotjak1,
- Rainer Landgraf1,
- Martin Hrabé de Angelis3,5,
- Florian Holsboer1, and
- Wolfgang Wurst1,2,4,6
- 1Max-Planck-Institut für Psychiatrie, D-80804 Munich, Germany,
- 2Institute of Developmental Genetics and
- 3Institute of Experimental Genetics, Helmholtz Zentrum München, D-85764 Neuherberg, Germany,
- 4Lehrstuhl für Entwicklungsgenetik,
- 5Lehrstuhl für Experimentelle Genetik, Technische Universität München, D-85350 Freising-Weihenstephan, Germany, and
- 6Deutsches Zentrum für Neurodegenerative Erkrankungen, München, D-80336 Munich, Germany
- Correspondence should be addressed to Jan M. Deussing, Molecular Neurogenetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2-10, D-80804 Munich, Germany. deussing{at}mpipsykl.mpg.de
Author contributions
Disclosures
- Received March 1, 2010.
- Revision received May 5, 2010.
- Accepted May 11, 2010.
This work was partially supported by the Bundesministerium für Bildung und Forschung within the framework of the Nationales Genomforschungsnetz Plus (FKZ: 01GS0850, 01GS08151, and 01GS08155), the European Commission (EUMODIC: LSHG-2006-037188), by the Initiative and Networking Fund of the Helmholtz Association in the framework of the Helmholtz Alliance for Mental Health in an Ageing Society (HA-215), and by Fonds der Chemischen Industrie. We thank Katja Mayer, Tanja Orschmann, Daniela Kohl, Jessica Koepke, and Ursula Habersetzer for excellent technical assistance. We thank Susanne Bourier and Sawoula Michailidou for blastocyst injection and generation of chimeric mice. We thank K. R. Thomas, P. Soriano, and P. Mombaerts for gifts of plasmids pACN, pROSA26-1, and ETLpA-/LTNL, respectively. We also thank the members of the German Mouse Clinic for comprehensive phenotyping of the mice and fruitful discussions. Moreover, we thank Carola Hetzel and Katharine Webb for critical comments on this manuscript.
- Correspondence should be addressed to Jan M. Deussing, Molecular Neurogenetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2-10, D-80804 Munich, Germany. deussing{at}mpipsykl.mpg.de
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