Article Information
- Received March 30, 2011
- Revision received April 28, 2011
- Accepted May 1, 2011
- First published June 29, 2011.
- Version of record published June 29, 2011.
Author Information
Author contributions
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Author contributions: Z.G., K.U., R.E.H., and J.H. designed research; Z.G., K.U., P.D., M.N., L.Y., J.M., and J.H. performed research; Z.G., K.U., P.D., M.N., L.Y., and J.H. analyzed data; Z.G. and J.H. wrote the paper.
Disclosures
- Received March 30, 2011.
- Revision received April 28, 2011.
- Accepted May 1, 2011.
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This work was supported by a Epilepsy Foundation Predoctoral Fellowship (K.U.), Welch Foundation Grant I-1660 (J.H.), Cancer Prevention and Research Institute of Texas Grant RP100674 (J.H.), and National Institutes of Health Grant AG032383 (J.H.). We thank Ling Zhang, Yan Jiang, Yindi Jiang, and Ridhima Chadha for technical assistance and Jose Cabrera for graphic support. We also thank Amelia Eisch for the Nestin–CreERT2 and Nestin–GFP mice, Jane Johnson for the Ascl1–GFP mice, Chun-li Zhang for assistance with in situ hybridization, and members of the Eisch, Johnson, and Zhang laboratories for helpful discussions on this manuscript. We are grateful to David Anderson for the 12C11 mouse monoclonal REST antibody and Sadhan Majumder for the REST–VP16 construct. We thank Fred Gage for exchanging information before publication and Eric Olson, Tomoko Kuwabara, and Ondine Cleaver for critical comments on this manuscript.
- Correspondence should be addressed to Jenny Hsieh, Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390. jenny.hsieh{at}utsouthwestern.edu
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