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Articles, Neurobiology of Disease

Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo

Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman and John R. Cirrito
Journal of Neuroscience 3 August 2011, 31 (31) 11328-11337; DOI: https://doi.org/10.1523/JNEUROSCI.0607-11.2011
Deborah K. Verges
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Jessica L. Restivo
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Whitney D. Goebel
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David M. Holtzman
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John R. Cirrito
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0607-11.2011
PubMed 
21813692
Published By 
Society for Neuroscience
History 
  • Received February 3, 2011
  • Revision received June 12, 2011
  • Accepted June 14, 2011
  • Published in print August 3, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3111328-10$15.00/0

Author Information

  1. Deborah K. Verges1,
  2. Jessica L. Restivo1,
  3. Whitney D. Goebel1,
  4. David M. Holtzman1,2,3,4, and
  5. John R. Cirrito1,3,4
  1. 1Departments of Neurology and
  2. 2Developmental Biology,
  3. 3Hope Center for Neurological Disorders, and
  4. 4Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, Missouri 63110
View Full Text

Author contributions

  1. Author contributions: D.K.V., D.M.H., and J.R.C. designed research; D.K.V., J.L.R., W.D.G., and J.R.C. performed research; J.L.R., W.D.G., and J.R.C. analyzed data; J.R.C. wrote the paper.

View Abstract

Disclosures

    • Received February 3, 2011.
    • Revision received June 12, 2011.
    • Accepted June 14, 2011.
  • We thank the National Institutes of Health/NIA (K01 AG029524 and P50 AG568127 to J.R.C.), the Shmerler family (J.R.C.), the Charles F. and Joanne Knight Alzheimer's Disease Research Center at Washington University (J.R.C.), the McDonnell Center for Cell and Molecular Biology (J.R.C.), Cure Alzheimer's Fund (D.M.H.), and Elison Medical Foundation (D.M.H.).

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to John R. Cirrito, Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110. cirritoj{at}neuro.wustl.edu

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The Journal of Neuroscience: 31 (31)
Journal of Neuroscience
Vol. 31, Issue 31
3 Aug 2011
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Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo
Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, John R. Cirrito
Journal of Neuroscience 3 August 2011, 31 (31) 11328-11337; DOI: 10.1523/JNEUROSCI.0607-11.2011

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Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo
Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, John R. Cirrito
Journal of Neuroscience 3 August 2011, 31 (31) 11328-11337; DOI: 10.1523/JNEUROSCI.0607-11.2011
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