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History
- Received May 23, 2011
- Revision received July 2, 2011
- Accepted July 28, 2011
- First published September 14, 2011.
- Version of record published September 14, 2011.
Copyright & Usage
Copyright © 2011 the authors 0270-6474/11/3113110-08$15.00/0
Author Information
- Kaoru Yamada1,
- John R. Cirrito1,
- Floy R. Stewart1,
- Hong Jiang1,
- Mary Beth Finn1,
- Brandon B. Holmes1,
- Lester I. Binder2,
- Eva-Maria Mandelkow3,
- Marc I. Diamond1,
- Virginia M.-Y. Lee4, and
- David M. Holtzman1
- 1Department of Neurology, Hope Center for Neurological Disorders, Alzheimer's Disease Research Center, Washington University, St. Louis, Missouri 63110,
- 2Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611,
- 3Max Planck Unit for Structural Molecular Biology, c/o DESY, 22607 Hamburg, Germany, and
- 4Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
Author contributions
Author contributions: K.Y., J.R.C., and D.M.H. designed research; K.Y., F.R.S., H.J., M.B.F., and B.B.H. performed research; H.J., B.B.H., L.I.B., E.-M.M., M.I.D., and V.M.-Y.L. contributed unpublished reagents/analytic tools; K.Y., J.R.C., F.R.S., M.B.F., and D.M.H. analyzed data; K.Y., M.I.D., V.M.-Y.L., and D.M.H. wrote the paper.
Disclosures
- Received May 23, 2011.
- Revision received July 2, 2011.
- Accepted July 28, 2011.
This work was supported by funding from AstraZeneca (D.M.H.), Cure Alzheimer's Fund (D.M.H.), Astellas Foundation for Research on Metabolic Disorders (K.Y.), the Uehera Memorial Foundation (K.Y.), and Japan Society for the Promotion of Science (K.Y.).
The authors declare no competing financial interests.
- Correspondence should be addressed to David M. Holtzman, Department of Neurology, Washington University, 425 South Euclid Avenue, BJCIH ninth floor, Campus Box 8111, St. Louis, MO 63110. holtzman{at}neuro.wustl.edu
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