Article Information
- Received March 10, 2011
- Revision received August 6, 2011
- Accepted August 10, 2011
- First published September 28, 2011.
- Version of record published September 28, 2011.
Author Information
Author contributions
Author contributions: L.W. and D.A.H. designed research; L.W. and J.A.T. performed research; L.W. contributed unpublished reagents/analytic tools; L.W. and D.A.H. analyzed data; L.W. and D.A.H. wrote the paper.
Disclosures
- Received March 10, 2011.
- Revision received August 6, 2011.
- Accepted August 10, 2011.
This work was supported by NIH Grants NS40975 and NS052526 (D.A.H.). Tg(F35) mice were obtained from Adriano Aguzzi (Institute of Neuropathology at the University of Zurich, Zurich, Switzerland), and Prn-p0/0 and Tga20 mice from Charles Weissmann (The Scripps Research Institute, Jupiter, FL). We thank Cheryl Adles and Su Deng for mouse maintenance and genotyping. We acknowledge Aimin Li for help with primer design and cloning, and advice on the course of the project. We are grateful to Michael Green and Richard Stewart for critically reading this manuscript. We appreciate help from Emiliano Biasini for work on the PIPLC release experiments.
- Correspondence should be addressed to David A. Harris, Department of Biochemistry, Boston University School of Medicine, 72 East Concord Street, K225, Boston, MA 02118. daharris{at}bu.edu
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