Article Information
- Received May 4, 2012
- Revision received August 2, 2012
- Accepted September 3, 2012
- First published November 14, 2012.
- Version of record published November 14, 2012.
Author Information
- Renaud La Joie1,2,3,4,
- Audrey Perrotin1,2,3,4,
- Louisa Barré6,
- Caroline Hommet7,8,9,
- Florence Mézenge1,2,3,4,
- Méziane Ibazizene6,
- Vincent Camus7,8,10,
- Ahmed Abbas1,2,3,4,
- Brigitte Landeau1,2,3,4,
- Denis Guilloteau7,8,11,
- Vincent de La Sayette1,2,3,5,
- Francis Eustache1,2,3,4,
- Béatrice Desgranges1,2,3,4, and
- Gaël Chételat1,2,3,4
- 1Institut National de la Santé et de la Recherche Médicale (Inserm), Unité 1077,
- 2Université de Caen Basse-Normandie, Unité Mixte de Recherche (UMR) S1077,
- 3Ecole Pratique des Hautes Etudes, UMR-S1077,
- 4Unité 1077 and
- 5Service de Neurologie, Centre Hospitalier Universitaire de Caen, and
- 6Laboratoire de Développements Méthodologiques en Tomographie par Emission de Positons, Commissariat à l'Energie Atomique/Division des Sciences de la Vie/Institut d'Imagerie Biomédicale, Centre d'Imagerie Cérébrale et de Recherche en Neurosciences (Cyceron), 14000 Caen, France,
- 7Université François Rabelais de Tours, UMR-S930 and Equipe de Recherche Labellisée 3106,
- 8Inserm, Unité 930,
- 9Centre Mémoire Ressources Recherche,
- 10Clinique Psychiatrique Universitaire, and
- 11Service de Médecine Nucléaire, Centre Hospitalier Régional et Universitaire de Tours, 37000 Tours, France
Author contributions
Author contributions: R.L.J., V.d.L.S., F.E., B.D., and G.C. designed research; R.L.J., A.P., F.M., V.d.L.S., F.E., B.D., and G.C. performed research; L.B., C.H., M.I., V.C., A.A., B.L., and D.G. contributed unpublished reagents/analytic tools; R.L.J., F.M., and B.L. analyzed data; R.L.J. and G.C. wrote the paper.
Disclosures
- Received May 4, 2012.
- Revision received August 2, 2012.
- Accepted September 3, 2012.
This study was funded by Agence Nationale de la Recherche (Longévité et Vieillissement 2007), Programme Hospitalier de Recherche Clinique (National 2008), Région Basse Normandie, and Institut National de la Santé et de la Recherche Médicale (Inserm), including the Inserm Liliane Bettencourt School (MD–PhD Program). We are grateful to M. Fouquet and N. Villain for their comments and support. We thank K. Mevel, H. Mirabel, M. Gaubert, S. Egret, A. Pélerin, C. Schupp, J. Dayan, A. Quillard, A. Manrique, C. Lebouleux, M. H. Noel, and M. C. Onfroy for their help in the data acquisition and the volunteers who participated in this study.
- Correspondence should be addressed to Dr. Gaël Chételat, Unité de Recherche U1077, Centre Cyceron, Boulevard H. Becquerel, Boîte Postale 5229, 14074 Caen, France. chetelat{at}cyceron.fr
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