Article Information
- Received April 3, 2012
- Revision received February 14, 2013
- Accepted February 22, 2013
- First published April 3, 2013.
- Version of record published April 3, 2013.
Author Information
- Wensheng Lin1,2,
- Yifeng Lin1,
- Jin Li1,
- Ali G. Fenstermaker3,
- Sharon W. Way3,
- Benjamin Clayton3,
- Stephanie Jamison1,
- Heather P. Harding4,
- David Ron4, and
- Brian Popko3
- 1Department of Cell Biology & Neuroscience, University of South Alabama College of Medicine, Mobile, Alabama 36688,
- 2Department of Comparative Medicine, University of South Alabama College of Medicine, Mobile, Alabama 36688,
- 3Department of Neurology, University of Chicago, Chicago, Illinois 60637, and
- 4University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Cambridge CB20QQ, United Kingdom
Author contributions
Author contributions: W.L. and B.P. designed research; W.L., Y.L., J.L., A.G.F., S.W.W., B.C., and S.J. performed research; H.P.H. and D.R. contributed unpublished reagents/analytic tools; W.L., Y.L., S.W.W., H.P.H., D.R., and B.P. analyzed data; W.L., B.C., and B.P. wrote the paper.
Disclosures
- Received April 3, 2012.
- Revision received February 14, 2013.
- Accepted February 22, 2013.
This work was supported by National Multiple Sclerosis Society Grants TA 3026-A-1 and RG-4813-A-2 to W.L., National Institutes of Health Grant NS34939 to B.P., and the Myelin Repair Foundation to B.P. This work used the Nikon A1 confocal microscope funded by National Institutes of Health Grant S10RR027535. We thank Dr. Wendy Macklin (University of Colorado Denver, Aurora, Colorado) for providing the proteolipid protein-based expression construct and Dr. M.A. Aryan Namboodiri (Uniformed Services University of the Health Sciences, Bethesda, Maryland) for providing the antibody against aspartoacylase.
The authors declare no competing financial interests.
- Correspondence should be addressed to either of the following: Dr. Wensheng Lin, Department of Neuroscience, University of Minnesota, 2101 6th Street SE, WMBB4-410, Minneapolis, MN 55455, linw{at}umn.edu; or Dr. Brian Popko, Center for Peripheral Neuropathy, Department of Neurology, University of Chicago, 5841 South Maryland Avenue, MC2030, Chicago, IL 60637, bpopko{at}neurology.bsd.uchicago.edu
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