Article Information
- Received April 3, 2013
- Revision received July 20, 2013
- Accepted July 23, 2013
- First published August 21, 2013.
- Version of record published August 21, 2013.
Author Information
- Xander Houbaert1,*,
- Chun-Lei Zhang1,*,
- Frédéric Gambino2,
- Marilyn Lepleux1,
- Melissa Deshors1,3,
- Elisabeth Normand3,
- Florian Levet4,
- Mariana Ramos5,
- Pierre Billuart5,
- Jamel Chelly5,
- Etienne Herzog1, and
- Yann Humeau1
- 1Team synapse in cognition, Institut Interdisciplinaire de Neuroscience, Centre National de la Recherche Scientifique CNRS UMR5297, Université de Bordeaux, 33077 Bordeaux, France,
- 2Institut des neurosciences cellulaires et intégratives, Centre National de la Recherche Scientifique CNRS UPR3212, Université de Strasbourg, 67000 France,
- 3Pole in vivo, Institut Interdisciplinaire de Neuroscience, Centre National de la Recherche Scientifique CNRS UMR5297, Université de Bordeaux, 33077 Bordeaux, France,
- 4Team imaging the cell, Institut Interdisciplinaire de Neuroscience, Centre National de la Recherche Scientifique CNRS UMR5297, Université de Bordeaux, 33077 Bordeaux, France, and
- 5Centre National de la Recherche Scientifique, Université Paris Descartes, Institut National de la Santé et de la Recherche Médicale, UMR8104, Institut Cochin, 75014 Paris, France
Author contributions
Author contributions: J.C. and Y.H. designed research; X.H., C.-L.Z., F.G., M.L., M.D., E.N., P.B., and Y.H. performed research; F.L., M.R., and P.B. contributed unpublished reagents/analytic tools; X.H., C.-L.Z., F.G., M.L., and Y.H. analyzed data; E.H. and Y.H. wrote the paper.
↵*X.H. and C.-L.Z. contributed equally to this work.
Disclosures
- Received April 3, 2013.
- Revision received July 20, 2013.
- Accepted July 23, 2013.
This work was supported by Agence Nationale pour la Recherche (J.C., E.H., and Y.H.), the European Neuroscience Institutes Network (Y.H.), and the Gencodys FP7 program (Y.H. and J.C.). We thank Drs Shona Osborne, Cyril Herry, Andréas Lüthi, Julien Dupuis, and François Georges for their critical reading of the manuscript; Dr. Jiyun Peng for helping in the tracking of mouse activities; and the Pole In Vivo and animal facilities of the Bordeaux University for the animal care. The microscopy was done at the Bordeaux Imaging Center of the University of Bordeaux Segalen, with the help of Sébastien Marais and Magali Mondin.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Yann Humeau, UMR5297 Institut Interdisciplinaire de Neuroscience, Centre de génomique fonctionnelle, 146 rue Léo Saignat, 33077, Bordeaux cedex, France. yann.humeau{at}u-bordeaux2.fr
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