Article Information
- Received July 27, 2013
- Revision received January 13, 2014
- Accepted January 30, 2014
- First published March 19, 2014.
- Version of record published March 19, 2014.
Author Information
Author contributions
Author contributions: D.C.-C., D.M.E., A.D.T.B., K.T.D., G.R.J., and R.K. designed research; D.C.-C., U.S., M.J.G.-M., C.L.-R., J.E.G., G.S., and R.K. performed research; R.K. contributed unpublished reagents/analytic tools; D.C.-C., U.S., M.J.G.-M., C.L.-R., J.E.G., G.S., D.M.E., A.D.T.B., K.T.D., G.R.J., and R.K. analyzed data; D.C.-C., U.S., J.E.G., A.D.T.B., G.R.J., and R.K. wrote the paper.
Disclosures
- Received July 27, 2013.
- Revision received January 13, 2014.
- Accepted January 30, 2014.
This work was supported by the Alzheimer's Drug Discovery Foundation, the Cullen Family Trust for Health Care, and the Mitchell Center for Neurodegenerative Diseases. We thank Shashirekha Krishnamurthy and Malika Farhed for excellent technical assistance; the University of Texas Medical Branch Rodent In Vivo Assessment Core (directed by Kelly T. Dineley) and Caterina Hernandez for assistance with experimental design and data analysis for the animal work; and Adriana Paulucci and Yogesh Wairkar for help with microscopy and image analysis.
R.K. has patent applications on the compositions and methods related to tau oligomers and antibodies. The remaining authors declare no competing financial interests.
- Correspondence should be addressed to Rakez Kayed, PhD, The University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555-1045. rakayed{at}utmb.edu
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