Article Information
- Received December 8, 2013
- Revision received November 1, 2014
- Accepted November 5, 2014
- First published January 7, 2015.
- Version of record published January 7, 2015.
Author Information
- Fanny Charbonnier-Beaupel1,2,3,4,*,
- Marion Malerbi1,2,3,5,6,*,
- Cristina Alcacer1,5,6,*,
- Khadija Tahiri1,2,3,
- Wassila Carpentier7,
- Chuansong Wang8,
- Matthew During8,
- Desheng Xu9,
- Paul F. Worley9,
- Jean-Antoine Girault1,5,6,
- Denis Hervé1,5,6,*, and
- Jean-Christophe Corvol1,2,3,10,*
- 1Sorbonne Universités, UPMC Univ Paris 06, Paris, France,
- 2Inserm, UMR-S 1127, ICM, Pitié-Salpêtrière Hospital, 75013 Paris, France,
- 3CNRS, UMR 7225, 75013 Paris, France,
- 4Assistance Publique Hôpitaux de Paris, Department of Pharmacy, Pitié-Salpêtrière Hospital, 75013 Paris, France,
- 5Inserm UMR-S 839, 75005 Paris, France,
- 6Institut du Fer à Moulin, 75005 Paris, France,
- 7UPMC Univ Paris 06, Post genomic platform P3S, 75013 Paris, France,
- 8Departments of Molecular Virology, Immunology and Medical Genetics, Neuroscience and Neurological Surgery, The Ohio State University, Columbus, Ohio 43210,
- 9Johns Hopkins University School of Medicine, Solomon H. Snyder Department of Neuroscience, Baltimore, Maryland 21205, and
- 10Assistance Publique Hôpitaux de Paris, Inserm, Clinical Investigation Center, CIC-1422, Pitié-Salpêtrière Hospital, 75013 Paris, France
Author contributions
Author contributions: F.C.-B., M.M., C.A., J.-A.G., D.H., and J.-C.C. designed research; F.C.-B., M.M., C.A., K.T., W.C., C.W., M.D., D.X., D.H., and J.-C.C. performed research; P.F.W. contributed unpublished reagents/analytic tools; F.C.-B., M.M., K.T., and J.-C.C. analyzed data; F.C.-B., M.M., C.A., K.T., W.C., C.W., M.D., D.X., P.F.W., J.-A.G., D.H., and J.-C.C. wrote the paper.
↵*F.C.-B., M.M., C.A., D.H., and J.-C.C. contributed equally to this work.
Disclosures
- Received December 8, 2013.
- Revision received November 1, 2014.
- Accepted November 5, 2014.
The work was supported by the University Pierre and Marie Curie (UPMC), Inserm (Grant Inserm/DHOS 2008), the Fondation pour la Recherche Médicale, the Société française de pharmacologie et de thérapeutique, the Agence Nationale de la Recherche (Grant ANR09-MNPS-014), the Michael Stern Parkinson's Research Foundation, and the European Research Council. The research leading to these results has received funding from the program “Investissements d'avenir” ANR-10-IAIHU-06. P.W. was supported by National Institutes of Health Grant R01 NS039156.; We thank the staff of the Institut du Fer a Moulin Imaging and animal facilities and the staff of the Plateforme post-genomique P3S facility at the Pitié-Salpêtrière Hospital. Analyses were performed using Biometric Research Branch ArrayTools developed by Dr. Richard Simon and BRB-ArrayTools Development Team.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Jean-Christophe CORVOL, ICM, Hôpital de la Pitié-Salpêtrière, 47 Bd de l'Hôpital, 75651 Paris Cedex 13, France. jean-christophe.corvol{at}psl.aphp.fr
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