Article Information
- Received October 8, 2015
- Revision received September 6, 2016
- Accepted September 7, 2016
- First published October 26, 2016.
- Version of record published October 26, 2016.
Author Information
- Karen Krukowski1,
- Niels Eijkelkamp3,4,*,
- Geoffroy Laumet1,*,
- C. Erik Hack3,
- Yan Li2,
- Patrick M. Dougherty2,
- Cobi J. Heijnen1, and
- Annemieke Kavelaars1
- 1Laboratory of Neuroimmunology, Division of Internal Medicine, and
- 2Department of Anesthesiology and Pain Medicine Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, and
- 3Laboratory of Translational Immunology, and
- 4Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, 3584EA Utrecht, The Netherlands
Author contributions
Author contributions: K.K., N.E., G.L., C.E.H., Y.L., P.M.D., C.J.H., and A.K. designed research; K.K., N.E., G.L., and Y.L. performed research; C.E.H. contributed unpublished reagents/analytic tools; K.K., N.E., G.L., C.E.H., Y.L., C.J.H., and A.K. analyzed data; K.K., N.E., C.E.H., P.M.D., C.J.H., and A.K. wrote the paper.
↵*N.E. and G.L. contributed equally to this work.
Disclosures
- Received October 8, 2015.
- Revision received September 6, 2016.
- Accepted September 7, 2016.
This work was supported by a STAR award from the University of Texas System and the National Institutes of Health (Grants R21 CA183736, RO1 NS073939, and RO1 NS074999 and National Cancer Institute Support Grant P30 CA016672 to MD Anderson Cancer Center). We thank Xiao Jiao Huo for technical assistance and Christine Steen-Louws for producing the IL-4/IL-10 synerkine fusion protein.
C.E.H. has a patent for the synerkine used in this study. The remaining authors declare no competing financial interests.
- Correspondence should be addressed to Annemieke Kavelaars, Laboratory of Neuroimmunology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 384, Houston, TX 77030. AKavelaars{at}mdanderson.org
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