Article Information
- Received October 14, 2016
- Revision received February 6, 2017
- Accepted February 27, 2017
- First published March 10, 2017.
- Version of record published April 12, 2017.
Author Information
- Lisa E. Pomeranz1,*,
- Mats I. Ekstrand1,*,
- Kaamashri N. Latcha2,
- Gregory A. Smith3,
- Lynn W. Enquist4,5, and
- Jeffrey M. Friedman1
- 1Laboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York 10065,
- 2Department of Biology, Graduate School of Arts and Science, New York University, New York, New York 10003,
- 3Department of Microbiology–Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, and
- 4Department of Molecular Biology and
- 5Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08544
Author contributions
Author contributions: L.E.P., M.I.E., and J.M.F. designed research; L.E.P., M.I.E., and K.N.L. performed research; L.E.P., M.I.E., G.A.S., L.E., and J.M.F. contributed unpublished reagents/analytic tools; L.E.P., M.I.E., and J.M.F. analyzed data; L.E.P., M.I.E., and J.M.F. wrote the paper.
↵*L.E.P. and M.I.E. contributed equally to this work.
Disclosures
- Received October 14, 2016.
- Revision received February 6, 2017.
- Accepted February 27, 2017.
This work was supported by the JPB Foundation, the National Institute of Drug and Alcohol Abuse (Grant RO1 DA018799), and the National Institutes of Health (Grant R01 AI056346 to G.A.S., Grant R01 NS060699 to L.W.E.). We thank Audrey Liu for her contributions to the cloning of the PRV-Bartha genome and to Sarah A. Stern for helpful discussion and her thoughtful comments on this manuscript. We are grateful to Nicholas Socci for his analysis of our anatomical tracing results and hierarchical spread of PRV.
The authors declare no competing financial interests.
- Correspondence should be addressed to Jeffrey M. Friedman Laboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065. friedj{at}mail.rockefeller.edu
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