Article Information
- Received January 31, 2017
- Revision received June 20, 2017
- Accepted June 29, 2017
- First published July 20, 2017.
- Version of record published September 6, 2017.
Author Information
- Wei Rose Xie1,2,3,
- Hsin-I Jen4,
- Michelle L. Seymour5,6,
- Szu-Ying Yeh1,4,
- Fred A. Pereira5,6,7,
- Andrew K. Groves3,4,8,
- Tiemo J. Klisch1,3, and
- Huda Y. Zoghbi1,2,3,4,9
- 1Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, Texas 77030,
- 2Program in Integrative Molecular and Biomedical Sciences,
- 3Department of Molecular and Human Genetics,
- 4Program in Developmental Biology,
- 5Huffington Center on Aging,
- 6Department of Molecular and Cellular Biology,
- 7Bobby R Alford Department of Otolaryngology, Head and Neck Surgery, and
- 8Department of Neuroscience, and
- 9Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas 77030
Author contributions
Author contributions: A.K.G., T.J.K., and H.Y.Z. designed research, reviewed data, and edited the manuscript; W.R.X., H.-I.J., M.L.S., S.-Y.Y., and F.A.P. performed research; W.R.X. and S.-Y.Y. analyzed data; W.R.X. wrote the paper.
Disclosures
- Received January 31, 2017.
- Revision received June 20, 2017.
- Accepted June 29, 2017.
This work was supported in part by the Neuropathology Core of the Jan and Dan Duncan Neurological Research Institute with expert assistance from Roy Sillitoe, Ph.D., and Tao Lin and also by the RNA In Situ and Microscopy and the Neurobehavioral Cores supported by a National Institutes of Health (NIH) Intellectual and Developmental Disabilities Research Centers Grant U54HD083092 (all cores) and a Shared Instrumentation Grant from the NIH (Grant 1S10OD016167 to the RNA In Situ and Microscopy Core) from the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The content is the sole responsibility of the authors and does not necessarily represent the official views of the Eunice Kennedy Shriver National Institute of Child Health and Human Development or the NIH. This project was also funded by the Cancer Prevention and Research Institute Texas (Grant RP110390 to T.J.K.) and NIH Grants DC006185 and DC014832 to A.K.G., H.Y.Z. is an investigator of the Howard Hughes Medical Institute. We thank the members of the Zoghbi laboratory and Vicky Brandt for helpful discussions and comments on the manuscript and Rende Gu, Ph.D., for technical support on adult cochlear dissection.
The authors declare no competing financial interests.
- Correspondence should be addressed to either of the following: Tiemo J. Klisch or Huda Y. Zoghbi, Department of Molecular and Human Genetics, Baylor College of Medicine, 1250 Moursund St. Ste. N1350, Houston, TX 77030. hzoghbi{at}bcm.edu or klisch{at}bcm.edu
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