Article Information
- Received May 10, 2017
- Revision received November 8, 2017
- Accepted November 30, 2017
- First published December 8, 2017.
- Version of record published January 24, 2018.
Author Information
- Courtney Thaxton1,2,*,
- Alexander D. Kloth1,2,*,
- Ellen P. Clark1,2,
- Sheryl S. Moy3,4,
- Raymond A. Chitwood5, and
- Benjamin D. Philpot1,2,4
- 1Department of Cell Biology and Physiology,
- 2Neuroscience Center,
- 3Department of Psychiatry,
- 4Carolina Institute for Developmental Disabilities, the University of North Carolina, Chapel Hill, North Carolina 27599, and
- 5Center for Learning and Memory, Department of Neuroscience, University of Texas, Austin, Texas 78712
Author contributions
Author contributions: C.T., A.D.K., S.S.M., R.A.C., and B.D.P. designed research; C.T., A.D.K., E.P.C., S.S.M., and R.A.C. performed research; C.T., A.D.K., S.S.M., and R.A.C. analyzed data; C.T., A.D.K., and B.D.P. wrote the paper.
↵*C.T. and A.D.K. contributed equally to this work.
Disclosures
- Received May 10, 2017.
- Revision received November 8, 2017.
- Accepted November 30, 2017.
This work was supported by the Pitt–Hopkins Research Foundation (B.D.P., C.T., and A.D.K.), University of Pennsylvania Orphan Disease Center Million Dollar Bike Ride (Grant MDBR-15-108-PH to B.D.P. and C.T.), the Brain and Behavior Research Foundation (NARSAD Young Investigator Grant 20653 to C.T.), and the National Institute of General Medical Sciences (Training, Workforce Development and Diversity Grant K12GM000678 to A.D.K.). Confocal imaging was supported by the National Institute of Neurological Disorders and Stroke (Grant P30NS045892) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD Grant U54HD79124). The mouse behavioral phenotyping core was supported by the NICHD (Grant U54HD079124 to S.S.M.). We thank Natallia Riddick and Viktoriya Nikolova for work on behavioral phenotyping, Dan Holmberg (Lund University, Sweden) for Tcf4Flox mice, and Tonis Timmusk (Tallinn University, Estonia) for luciferase constructs.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Benjamin D. Philpot, University of North Carolina School of Medicine, 115 Mason Farm Road, Chapel Hill, NC 27599-7545. bphilpot{at}med.unc.edu
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