Article Information
- Received April 25, 2018
- Revision received October 8, 2018
- Accepted October 12, 2018
- First published November 30, 2018.
- Version of record published January 9, 2019.
Author Information
- Guillaume Trébuchet1,2,3,4,*,
- Pierre B. Cattenoz1,2,3,4,*,
- János Zsámboki1,2,3,4,
- David Mazaud5,
- Daria E. Siekhaus6,
- Manolis Fanto5, and
- Angela Giangrande1,2,3,4
- 1Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France,
- 2Centre National de la Recherche Scientifique, UMR7104, 67400 Illkirch, France,
- 3Institut National de la Santé et de la Recherche Médicale, U964, 67400 Illkirch, France,
- 4Université de Strasbourg, 67404 Illkirch, France,
- 5Department of Basic and Clinical Neuroscience, King's College London, London SE5 9NU, United Kingdom, and
- 6Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria
Author contributions
Author contributions: G.T. designed research; G.T., P.B.C., and D.M. performed research; D.E.S. contributed unpublished reagents/analytic tools; G.T., P.B.C., J.Z., D.M., M.F., and A.G. analyzed data; A.G. wrote the paper.
↵*G.T. and P.B.C. contributed equally to this work.
Disclosures
- Received April 25, 2018.
- Revision received October 8, 2018.
- Accepted October 12, 2018.
This work was supported by INSERM, CNRS, UDS, Ligue Régionale contre le Cancer, Hôpital de Strasbourg, Association pour la Recherche sur le Cancer (ARC) and Agence Nationale de la Recherche (ANR) grants. P.B.C. was funded by the ANR and by the ARSEP (Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques), and G.T. by governmental and ARC fellowships. This work was also supported by grants from the Ataxia UK (2491) and the NC3R (NC/L000199/1) awarded to M.F. The Institut de Génétique et de Biologie Moléculaire et Cellulaire was also supported by a French state fund through the ANR labex. D.E.S. was funded by Marie Curie Grant CIG 334077/IRTIM. We thank B. Altenhein, K. Brückner, M. Crozatier, L. Waltzer, M. Logan, E. Kurant, R. Reuter, E. Kurucz, J.L Dimarcq, J. Hoffmann, C. Goodman, the DHSB, and the BDSC for reagents and flies. We also thank all of the laboratory members for comments on the manuscript; C. Diebold, C. Delaporte, M. Pezze, the fly, and imaging and antibody facilities for technical assistance; and D. Dembele for help with statistics. In addition, we thank Alison Brewer for help with Luciferase assays.
The authors declare no competing financial interests.
- Correspondence should be addressed to Angela Giangrande, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France. angela{at}igbmc.fr
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