Article Information
- Received July 20, 2016
- Revision received September 21, 2016
- Accepted November 4, 2016
- First published November 11, 2016.
- Version of record published January 4, 2017.
Author Information
- Valentina Lacovich1,2,*,
- Sonia L. Espindola3,*,
- Matías Alloatti1,*,
- Victorio Pozo Devoto1,
- Lucas E. Cromberg1,
- Mária E. Čarná2,
- Giancarlo Forte2,
- Jean-Marc Gallo4,
- Luciana Bruno5,
- Gorazd B. Stokin2,
- M. Elena Avale3, and
- Tomás L. Falzone1,6
- 1Instituto de Biología Celular y Neurociencias (IBCN-CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires CP 1121, Argentina,
- 2Centre for Translational Medicine (CTM), International Clinical Research Center, St. Anne's University Hospital (ICRC-FNUSA), Brno 65691, Czech Republic,
- 3Instituto de Investigaciones en Ingeniería Genética y Biología Molecular (INGEBI-CONICET), Buenos Aires C1428ADN, Argentina,
- 4Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, United Kingdom,
- 5Departamento de Física (IFIBA-CONICET), Facultad de Ciencias Exactas y Naturales (UBA), Buenos Aires C1428EGA, Argentina, and
- 6Instituto de Biología y Medicina Experimental (IBYME-CONICET), Buenos Aires C1428ADN, Argentina
Author contributions
Author contributions: J.-M.G., L.B., G.B.S., M.E.A., and T.L.F. designed research; V.L., S.L.E., M.A., V.P.D., L.E.C., M.E.A., and T.L.F. performed research; G.F. contributed unpublished reagents/analytic tools; S.L.E., M.A., M.C., L.B., M.E.A., and T.L.F. analyzed data; M.E.A. and T.L.F. wrote the paper.
↵*V.L., S.L.E., and M.A. contributed equally to this work.
Disclosures
- Received July 20, 2016.
- Revision received September 21, 2016.
- Accepted November 4, 2016.
This work was supported by Ministerio Nacional de Ciencia y Tecnología (Grant PICT 2013-0402 to T.L.F and Grant PICT2013-1109 to M.E.A.), the Alzheimer Association (Grant NIRG10-172840 to T.L.F.), Universidad de Buenos Aires (Grant UBACyT 2011/2014 to T.L.F.), the International Brain Research Organization (M.E.A), International Society for Neurochemistry-CAEN (M.E.A), and the European Regional Development Fund Project FNUSA-ICRC (Grants CZ.1.05/1.1.00/02.0123 and LQ1605 to G.B.S.). T.L.F and M.E.A were supported by Consejo Nacional de Investigaciones Científicas y Técnicas, University of Buenos Aires, and the Argentinean Science Ministry. S.L.E., V.P.D., M.A., and L.E.C. receive fellowships from CONICET. We thank Drs. Mariela Sued and Daniela Rodríguez for help with the statistical analysis of the data; Roux-Ocefa Argentina for kindly contributing basic reagents, and Fundación Rene Baron for donations.
The authors declare no competing financial interests.
- Correspondence should be addressed to either of the following: Tomás L. Falzone, Instituto de Biología Celular y Neurociencias (IBCN-CONICET-UBA), Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires CP 1121, Argentina, tfalzone{at}fmed.uba.ar; or M. Elena Avale, Instituto de Investigaciones en Ingeniería Genética y Biología Molecular (INGEBI-CONICET), Vuelta de Obligado 2490, Buenos Aires C1428ADN, Argentina. elena.avale{at}conicet.gov.ar
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