Article Information
- Received July 10, 2017
- Revision received March 28, 2018
- Accepted April 6, 2018
- First published April 16, 2018.
- Version of record published May 9, 2018.
Author Information
- Kazuma Fujikake1,2,*,
- Masato Sawada1,*,
- Takao Hikita1,
- Yayoi Seto1,
- Naoko Kaneko1,
- Vicente Herranz-Pérez3,4,
- Natsuki Dohi1,
- Natsumi Homma1,
- Satoshi Osaga5,
- Yuchio Yanagawa6,
- Toshihiro Akaike7,
- Jose Manuel García-Verdugo3,
- Mitsuharu Hattori8,
- Kazuya Sobue2, and
- Kazunobu Sawamoto1,9
- 1Departments of Developmental and Regenerative Biology,
- 2Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan,
- 3Laboratorio de Neurobiología Comparada, Instituto Cavanilles, Universidad de Valencia, CIBERNED, 46980 Valencia, Spain,
- 4Predepartamental Unit of Medicine, Faculty of Health Sciences, Universitat Jaume I, 12071 Castelló de la Plana, Spain,
- 5Clinical Research Management Center, Nagoya City University Hospital, Nagoya 467-8601, Japan,
- 6Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan,
- 7Biomaterials Center for Regenerative Medical Engineering, Foundation for Advancement of International Science, Tsukuba 305-0821, Japan,
- 8Department of Biomedical Science, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan, and
- 9Division of Neural Development and Regeneration, National Institute for Physiological Sciences, Okazaki 444-8585, Japan
Author contributions
Author contributions: K.F., M.S., T.H., N.K., J.M.G.-V., M.H., and K. Sawamoto designed research; K.F., M.S., T.H., Y.S., N.K., V.H.-P., N.D., N.H., Y.Y., T.A., J.M.G.-V., M.H., and K. Sobue performed research; K.F., M.S., T.H., Y.S., N.K., V.H.-P., N.D., N.H., S.O., J.M.G.-V., M.H., and K. Sawamoto analyzed data; K.F., M.S., and K. Sawamoto wrote the paper.
↵*K.F. and M.S. contributed equally to this work.
Disclosures
- Received July 10, 2017.
- Revision received March 28, 2018.
- Accepted April 6, 2018.
This work was supported by research grants from Funding Program for Next Generation World-Leading Researchers (NEXT) (Grant LS104), the Ministry of Education, Culture, Sports, Science and Technology Grants-in-Aid for Scientific Research [22122004 (to K. Sawamoto)], Japan Society for the Promotion of Science (JSPS) KAKENHI [Grants 26250019, 16H06280, 17H01392, 17H05750, and 17H05512 (to K. Sawamoto)], the JSPS Program for Advancing Strategic International Networks to Accelerate the Circulation of Talented Researchers [Grant S2704 (to M.S., N.K., V.H-P., J.M.G-V., and K. Sawamoto)], Bilateral Open Partnership Joint Research Projects (to K.S.), the Terumo Foundation for Life Sciences and Arts (to K.S.), Grant-in-Aid for Research at Nagoya City University (to K.S.), and the Takeda Science Foundation (to K.S.). We thank the Screening Committee of Anticancer Drugs supported by a Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Support Programs for Cancer Research (MEXT, Japan) for providing the SCADS Inhibitor Kits; K. Nakajima for the anti-ApoER2 antibody; H. Jinnou for the N-Cadhering-KD plasmids; I. Nomura, H. Takase, T. Miyamoto, and I. Miyoshi for technical support; and Sawamoto laboratory members for discussions.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Kazunobu Sawamoto, Department of Developmental and Regenerative Biology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8601, Japan. sawamoto{at}med.nagoya-cu.ac.jp
Other Version
- previous version (April 16, 2018).
- You are viewing the most recent version of this article.
Online Impact