J. Neurosci. Seahorse Bioscience

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Cover Figure


Cover picture: The distribution of tyrosinated tubulin (green) and acetylated tubulin (red) in the growth cone and distal neurite (differential interference contrast) derived from a rat superior cervical ganglion explant grown in a low concentration of nocodazole. Nocodazole alters the distribution of these two tubulin isoforms and also affects the distribution of microtubule endings in the growth cone. Microtubule staining in the growth cone was traced and is depicted to emphasize the extent of acetylated microtubule staining. The neurite staining is rendered so that the brightest staining of each chromophore is at saturation. Thus, the tyrosinated staining is at its brightest in the growth cone and decreases proximally, whereas the acetylated staining increases in intensity proximally. For details, see the article by Rochlin et al. in this issue (pp. 3236-3246).
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