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Cover picture: The distribution of tyrosinated tubulin
(green) and acetylated tubulin (red) in the
growth cone and distal neurite (differential interference contrast)
derived from a rat superior cervical ganglion explant grown in a low
concentration of nocodazole. Nocodazole alters the distribution of
these two tubulin isoforms and also affects the distribution of
microtubule endings in the growth cone. Microtubule staining in the
growth cone was traced and is depicted to emphasize the extent of
acetylated microtubule staining. The neurite staining is rendered so
that the brightest staining of each chromophore is at saturation. Thus,
the tyrosinated staining is at its brightest in the growth cone and
decreases proximally, whereas the acetylated staining increases in
intensity proximally. For details, see the article by Rochlin et al. in
this issue (pp. 3236-3246).
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